LEADER 05223nam 2200613Ia 450 001 9910139948803321 005 20200520144314.0 010 $a1-282-23751-9 010 $a9786612237515 010 $a0-470-71222-8 010 $a0-470-71221-X 035 $a(CKB)1000000000790570 035 $a(EBL)454338 035 $a(OCoLC)648761631 035 $a(SSID)ssj0000354549 035 $a(PQKBManifestationID)11212590 035 $a(PQKBTitleCode)TC0000354549 035 $a(PQKBWorkID)10302801 035 $a(PQKB)11153375 035 $a(MiAaPQ)EBC454338 035 $a(EXLCZ)991000000000790570 100 $a20080919d2008 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 00$aObesity $escience to practice /$f[edited by] Gareth Williams, Gema Fruhbeck 210 $aChichester, West Sussex, UK ;$aHoboken, NJ $cWiley$d2008 215 $a1 online resource (605 p.) 300 $aDescription based upon print version of record. 311 $a0-470-01911-5 320 $aIncludes bibliographical references and index. 327 $aObesity: Science to Practice; Contents; Preface; Contributors; 1 History of Obesity; Early human history; History of the biology of obesity; Descriptions and measurements of obesity; Metabolism and energy balance; Health hazards of obesity; Causes of obesity; Treatment of obesity; Growth of the scientifi c community; References; 2 Epidemiology and Social Impact of Obesity; Definitions of obesity; Current and recent prevalences of obesity; Childhood obesity; Predicted increases in obesity in adults; Comorbidities of obesity; Costs of obesity to society; Conclusions; References 327 $a3 Key Methodologies in Obesity Research and PracticeAnthropometric indices; Measurements of body composition; Measurements of fat distribution; Measuring energy balance; Assessing insulin sensitivity; References; 4 Adipose Tissue: Development, Anatomy and Functions; Introduction; Development of white adipose tissue; Structure of white adipose tissue; Fat storage and mobilization; Adipokines; Receptors expressed by adipose tissue; Brown adipose tissue; Adipose tissue development and dynamics; References; 5 The Regulation of Energy Balance: An Overview; Regulation of body fat and composition 327 $aRegulation of energy intake and expenditureLessons from other species: informative or misleading?; Causes of obesity; References; 6 Control of Eating; Flavour and orosensory signals; Gut signals; Metabolic signals; Adiposity signals; The neuroanatomy of eating regulation; The neuropharmacology of eating control; Modulating factors; References; 7 Energy Balance in Humans; Energy balance; Energy intake; Energy expenditure; Altered sympathetic activity in obesity; Substrate oxidation and predisposition to obesity; References; 8 Aetiology of Human Obesity; Lifestyle-related obesity 327 $aChanges in the prevalence of obesity over timeDrug-induced obesity; Endocrine causes of obesity; Specific genetic disorders; References; 9 Health Hazards of Obesity: An Overview; Measures of obesity as predictors of morbidity and mortality; Obesity and premature mortality; Cardiovascular disease; Type 2 diabetes; Malignancy; Gall-bladder disease; Osteoarthritis; Chronic renal failure; Ethnic differences in obesity-related predictors of disease; Conclusions; References; 10 Metabolic Complications of Obesity; Type 2 diabetes; The metabolic syndrome; Obesity and insulin resistance 327 $aObesity and the development of type 2 diabetesDyslipidaemia in obesity and the metabolic syndrome; References; 11 Liver Disease in Obesity; Epidemiology; Pathogenesis of NAFLD in obesity; Pathology of NAFLD; Natural history of NAFLD; Clinical presentation; Investigation of suspected NAFLD; Management of patients with NAFLD; References; 12 Cardiovascular Disease and Obesity; General links between obesity and cardiovascular disease; Impact of obesity on the heart; Obesity and hypertension; Obesity and congestive heart failure; Obesity and coronary artery disease; Obesity and arrhythmias 327 $aCardiac-associated adipose tissue 330 $aThis comprehensive textbook addresses one of the major public health concerns of our era - obesity. Clearly and simply, Obesity: science to practice provides a balanced, coherent account of obesity: how to define and measure it, its epidemiology, the physiological basis, associated diseases, how to assess, manage and treat it, and also strategies for prevention. The book is generously illustrated, including graphs and flow charts for easy reference. The chapters cite key references so that interested readers may pursue a given topic in more detail. Well presented and thoroughly e 606 $aObesity$vTextbooks 606 $aMetabolism$xDisorders$vTextbooks 615 0$aObesity 615 0$aMetabolism$xDisorders 676 $a616.85/26 701 $aWilliams$b Gareth$cMD.$0285738 701 $aFruhbeck$b Gema$00 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910139948803321 996 $aObesity$92250816 997 $aUNINA