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100   $a20090305d2009      uy             0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 00$aPeripheral receptor targets for analgesia$b[electronic resource] $enovel approaches to pain treatment /$fedited by Brian E. Cairns
210   $aHoboken, N.J. $cJohn Wiley & Sons$dc2009
215   $a1 online resource (566 p.)
300   $aIncludes index.
311   $a0-470-25131-X 
327   $aPERIPHERAL RECEPTOR TARGETS FOR ANALGESIA; CONTENTS; FOREWORD; PREFACE; CONTRIBUTORS; PART I PERIPHERAL MECHANISM IN CLINICAL PAIN CONDITIONS; 1. Role of Peripheral Mechanisms in Craniofacial Pain Conditions; 2. Role of Peripheral Mechanisms in Spinal Pain Conditions; PART II SPECIFIC RECEPTOR TARGETS FOR PERIPHERAL ANALGESICS; 3. Voltage-Gated Sodium Channels in Peripheral Nociceptive Neurons as Targets for the Treatment of Pain; 4. Potassium Channels; 5. Voltage-Gated Calcium Channels as Targets for the Treatment of Chronic Pain; 6. Adenosine Receptors; 7. Acid-Sensing Ion Channels and Pain
327   $a8. Vanilloid (TRPV1) and Other Transient Receptor Potential Channels9. Glutamate Receptors; 10. Serotonin Receptors; 11. Adrenergic Receptors; 12. Cholinergic Receptors and Botulinum Toxin; 13. Cannabinoids and Pain Control in the Periphery; 14. Opioid Receptors; 15. Calcitonin Gene-Related Peptide and Substance P; 16. Role of Somatostatin and Somatostatin Receptors in Pain; 17. Cytokines (Tumor Necrosis Factor, Interleukins) and Prostaglandins; 18. Neurotrophic Factors and Pain; PART III DELIVERY SYSTEMS; 19. Topical and Systemic Drug Delivery Systems for Targeted Therapy
327   $a20. Gene Therapy for Pain21. Topical Analgesics; Index
330   $aA unique reference on peripheral pain receptor mechanisms While considerable advances have been made on pharmacotherapies for many chronic disease states, options available to treat chronic pain have remained relatively unchanged for decades. However, utilizing the receptors involved in peripheral pain transduction mechanisms offers a significant opportunity to create novel therapies for pain. A comprehensive review of peripheral pain mechanisms, Peripheral Receptor Targets for Analgesia: Novel Approaches to Pain Management provides a unique resource that brings together a bo
606   $aNociceptors
606   $aNerves, Peripheral
606   $aAnalgesia
606   $aAnalgesics
606   $aPain
615  0$aNociceptors.
615  0$aNerves, Peripheral.
615  0$aAnalgesia.
615  0$aAnalgesics.
615  0$aPain.
676   $a615.783
676   $a616/.0472
701   $aCairns$b Brian E$0854336
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801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910139792203321
996   $aPeripheral receptor targets for analgesia$91907768
997   $aUNINA