LEADER 05492nam 2200673Ia 450 001 9910139761803321 005 20230721022729.0 010 $a1-282-34957-0 010 $a9786612349577 010 $a0-470-74810-9 010 $a0-470-74809-5 035 $a(CKB)1000000000793109 035 $a(EBL)454319 035 $a(OCoLC)609843806 035 $a(SSID)ssj0000303312 035 $a(PQKBManifestationID)11228539 035 $a(PQKBTitleCode)TC0000303312 035 $a(PQKBWorkID)10275197 035 $a(PQKB)11599910 035 $a(MiAaPQ)EBC454319 035 $a(Au-PeEL)EBL454319 035 $a(CaPaEBR)ebr10323387 035 $a(CaONFJC)MIL234957 035 $a(EXLCZ)991000000000793109 100 $a20090423d2009 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aMiniaturization of analytical systems$b[electronic resource] $eprinciples, designs and applications /$fAngel Rios, Alberto Escarpa, Bartolome? Simonet 210 $aHoboken, N.J. $cWiley$d2009 215 $a1 online resource (385 p.) 300 $aDescription based upon print version of record. 311 $a0-470-06110-3 320 $aIncludes bibliographical references and index. 327 $aMiniaturization of Analytical Systems: Principles, Designs and Applications; Contents; Preface; 1 Miniaturization in Analytical Chemistry; 1.1 Introduction; 1.2 Miniaturization as One of the Critical Trends in Modern Analytical Chemistry; 1.3 Evolution in the Field of Analytical Miniaturization; 1.4 Classification of Miniaturized Analytical Systems and Definition of Terms; 1.5 Theory of Miniaturization; 1.6 Features of Miniaturized Analytical Systems; 1.7 Incidences of Miniaturization in the Analytical Process; 1.7.1 Miniaturization of the Steps of the Analytical Process 327 $a1.7.2 Integrated (Micro)systems for the Performance of the Entire Analytical Process1.8 Outlook; References; 2 Tools for the Design of Miniaturized Analytical Systems; 2.1 Introduction; 2.2 Miniaturized Analytical Processes: The Downsizing and Integrating Phenomena; 2.2.1 Transport within Microfluidic Systems; 2.2.2 Microsystem Design from Transport Parameter Information; 2.3 Microfluidic Devices; 2.3.1 Microvalves; 2.3.2 Moving Liquids in Miniaturized Systems; 2.3.3 Mixers; 2.3.4 Volume-dispensing and Sample-introduction Devices; 2.3.5 Detection Systems for Analytical Microsystems 327 $a2.4 Microtechnology2.4.1 Computer Simulations in Microfluidics; 2.4.2 Micromachining; 2.4.3 Packaging of Microsystems; 2.5 MEMS and NEMS; 2.5.1 Fabrication and Characterization; 2.5.2 Functionalization; 2.5.3 Detection Methods; 2.6 Outlook; References; 3 Automation and Miniaturization of Sample Treatment; 3.1 Introduction; 3.2 Simplification of Sample Treatment: Microextraction Techniques; 3.2.1 Calibration in Microextraction Processes; 3.2.2 Solid Phase Microextraction (SPME) Techniques; 3.2.3 Liquid Phase Microextraction (LPME) Techniques 327 $a3.2.4 Comparison of Solid and Liquid Phase Microextraction Techniques3.3 Simplification of Sample Treatment: Continuous Flow Systems; 3.3.1 Coupling to Gas Chromatography; 3.3.2 Coupling to Liquid Chromatography; 3.3.3 Coupling to Capillary Electrophoresis (CE); References; 4 Miniaturized Systems for Analytical Separations I: Systems Based on a Hydrodynamic Flow; 4.1 Introduction; 4.2 The Earliest Example of Miniaturization of a Gas Chromatograph and Some Other Developments; 4.3 Capillary Liquid Chromatography (CLC); 4.4 Liquid Chromatography on Microchips; 4.4.1 The Agilent HPLC Chip 327 $a4.4.2 Other Approaches to Microchip HPLC4.4.3 Some Selected Applications; References; 5 Miniaturized Systems for Analytical Separations II: Systems Based on Electroosmotic Flow (EOF); 5.1 Introduction; 5.2 CE on the Microchip Format; 5.3 Modes and Theories of CE Microchips; 5.4 Microfabrication Techniques; 5.4.1 Microfabrication of Glass CE Microchips; 5.4.2 Microfabrication of Polymer CE Microchips; 5.5 Basic Fluidic Manipulation/Motivation: Electrokinetic Injection and Separation Protocols; 5.6 Electrochromatography in Microchip Format: Designs and Applications 327 $a5.7 Comparison of Hydrodynamic and Electroosmotic Flow-driven Miniaturized Systems 330 $aThe book describes a general vision of the miniaturization of the analytical systems, including their principles, designs and applications. Through ten chapters the different aspects characterizing the miniaturized systems are developed. Thus, the two first chapters include the basic concepts behind miniaturization in analytical chemistry, as well as the mechanical and electronic tools needed for designing and fabricating miniaturized analytical systems. Chapters 3 to 6 represent the core of the book, as they take as the basis the analytical process and deal with the miniaturization of sample 606 $aChemistry, Analytic 606 $aMiniature electronic equipment 615 0$aChemistry, Analytic. 615 0$aMiniature electronic equipment. 676 $a543 676 $a543.22 700 $aRi?os Castro$b Angel$0923199 701 $aEscarpa Miguel$b Alberto$f1968-$0923200 701 $aSimonet$b Bartolome?$0923201 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910139761803321 996 $aMiniaturization of analytical systems$92071599 997 $aUNINA