LEADER 03352nam  2200613Ia 450 
001 9910139747703321
005 20230725053937.0
010   $a0-470-95988-6
010   $a0-470-95991-6
010   $a0-470-95987-8
035   $a(CKB)2550000000066449
035   $a(EBL)661588
035   $a(OCoLC)742333099
035   $a(SSID)ssj0000851238
035   $a(PQKBManifestationID)12368609
035   $a(PQKBTitleCode)TC0000851238
035   $a(PQKBWorkID)10838469
035   $a(PQKB)10331280
035   $a(SSID)ssj0000614210
035   $a(PQKBManifestationID)11405557
035   $a(PQKBTitleCode)TC0000614210
035   $a(PQKBWorkID)10604307
035   $a(PQKB)11161164
035   $a(MiAaPQ)EBC661588
035   $a(EXLCZ)992550000000066449
100   $a20101109d2011      uy             0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 10$aComparative pharmacokinetics$b[electronic resource] /$fJim E. Riviere
205   $a2nd ed.
210   $aChichester, West Sussex $cWiley-Blackwell$dc2011
215   $a1 online resource (1038 p.)
300   $aDescription based upon print version of record.
311   $a0-8138-2138-X 
311   $a0-8138-2993-3 
320   $aIncludes bibliographical references and index.
327   $aMachine generated contents note: Preface.Chapter 1: Introduction.Chapter 2: Principles of Drug Movement in the Body.Chapter 3: Quantitative Structure Permeability Relationships (QSPeR).Chapter 4: Absorption. Chapter 5: Distribution. Chapter 6: Renal Elimination. Chapter 7: Hepatic Biotransformation and Biliary Excretion. Chapter 8: Compartmental Models. Chapter 9: Noncompartmental Models. Chapter 10: Nonlinear Models. Chapter 11: Physiological Models. Chapter 12: Dosage Regimens. Chapter 13: Simultaneous Pharmacokinetic-Pharmacodynamic Modeling. Chapter 14: Study Design and Data Analysis. Chapter 15: Design and Analysis of Bioequivalence Studies and FDA's in vitro/in vivo (IVIV). Chapter 16: Population Pharmacokinetic Models and the Bayesian Forecasting Applied to Clinical Pharmacokinetics. Chapter 17: Dosage Adjustments in Renal (and Hepatic) Disease. Chapter 18: Interspecies Extrapolations. Chapter 19: Tissue Residues and Withdrawal TimesAppendix.
330   $a"Now in a newly revised edition, Comparative Pharmacokinetics presents the principles and techniques of pharmacokinetics in a detailed, yet practical and easily understandable manner. Coverage includes an overview of the basic physiologic processes of drug absorption and disposition and detailed explanation of pharmacokinetic means of measuring and predicting these processes by way of mechanistic and empirical models, as well as extensive coverage of dosage regimens and adjustments, interspecies extrapolation, experimental design, data collection and analysis, and residues and withdrawal times"--Provided by publisher.
606   $aPharmacokinetics
606   $aVeterinary pharmacology
615  0$aPharmacokinetics.
615  0$aVeterinary pharmacology.
676   $a615.7
700   $aRiviere$b J. Edmond$g(Jim Edmond)$0519183
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910139747703321
996   $aComparative pharmacokinetics$9843582
997   $aUNINA