LEADER 04912nam 2200637Ia 450 001 9910139698603321 005 20230802004102.0 010 $a1-283-33303-1 010 $a9786613333032 010 $a1-118-26030-9 010 $a1-118-26047-3 010 $a1-118-26054-6 035 $a(CKB)2550000000061708 035 $a(EBL)818338 035 $a(OCoLC)769189209 035 $a(SSID)ssj0000542075 035 $a(PQKBManifestationID)11320655 035 $a(PQKBTitleCode)TC0000542075 035 $a(PQKBWorkID)10523988 035 $a(PQKB)10189390 035 $a(MiAaPQ)EBC818338 035 $a(Au-PeEL)EBL818338 035 $a(CaPaEBR)ebr10510493 035 $a(CaONFJC)MIL333303 035 $a(EXLCZ)992550000000061708 100 $a20110822d2012 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aTranslational neuroscience$b[electronic resource] $ea guide to a successful program /$fedited by Edgar Garcia-Rill 210 $aChichester, West Sussex, UK $cWiley-Blackwell$dc2012 215 $a1 online resource (178 p.) 300 $aDescription based upon print version of record. 311 $a0-470-96071-X 320 $aIncludes bibliographical references and index. 327 $aTranslational Neuroscience : A Guide to a Successful Program; Contents; Contributors; Preface; Acknowledgments; 1 A Brief History of Translational Neuroscience; Some recent history; Funding translational research; Lack of funding; Making NIH funding more equitable and efficient; How much funding is needed?; Medical research funding in Europe; References; 2 Mentoring in Translational Neuroscience; T1 blocks; T2 blocks; References; 3 Core Facilities for Translational Neuroscience; Designing translational neuroscience core facilities; Preattentional measure-the P50 potential 327 $aAttentional measures-psychomotor vigilanceFrontal lobe blood flow measures; References; 4 Translational Studies Using TMS; Overview; Introduction; Development of a sham stimulation technique for humans; PET-guided TMS studies of tinnitus perception; TMS investigations of decision-making in tobacco addiction; TMS investigations in rodents; Conclusion; References; 5 Translational Studies in Drug Abuse; Background and significance; Behavioral Core Facility; Voltage-sensitive dye imaging; Intravenous drug self-administration; References; 6 Electrophysiology in Translational Neuroscience 327 $aIn vivo and in vitro animal modelsModafinil; Patch clamp recordings; Gamma band activity; Population responses; Preconscious awareness; Magnetoencephalography, the Cadillac of human electrophysiology; References; 7 Translational Research on Spinal Cord Injury; Electrophysiological approach: H-reflex frequency-dependent depression; Biomechanical approach: windup of the stretch reflex; Interventions: passive exercise; Interventions: pharmacology (L-Dopa, Modafinil); Conclusions; References; 8 Translational Research in Neonatology; Introduction; The need for neonatal research 327 $aThe building blocks: basic researchPups to babies and back again: T1 Research; No problem can be solved unless it is first identified; From the bedside to the community: T2 research; The role of comparative effectiveness research; Barriers and rewards in translational research in neonatology; Opportunities for translational research in neonatology; Conclusion; References; 9 Telemedicine in Translational Neuroscience; History of telemedicine; Enabling access to care; Telemedicine Core Facility; Neonatal intensive care; Emergency departments; Conclusion; References 327 $a10 Implications for the FutureFragmented infrastructure; Incompatible databases; The benefits of translational research; The reshaping of basic science departments; References; Index; Color plates appear between pages 96 and 97. 330 $aTranslational research looks to take the latest innovations made in the laboratory setting to translate findings into effective and sustainable medical interventions and improved preventative measures. Funding support is increasingly tied to practical healthcare outcomes, with this trend likely only to increase in coming years, Translational Neuroscience: A Guide to a Successful Program, is a timely guide to developing research programs that bring translational advances to the forefront. Translational Neuroscience provides practical information from scientists with first-hand e 606 $aNeurosciences$xResearch 606 $aNeurosciences 615 0$aNeurosciences$xResearch. 615 0$aNeurosciences. 676 $a362.196/80072 701 $aGarcia-Rill$b Edgar$0945023 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910139698603321 996 $aTranslational neuroscience$92133436 997 $aUNINA