LEADER 04116nam 22006973u 450 001 9910139693803321 005 20230802005304.0 010 $a1-118-35818-X 010 $a1-283-54246-3 010 $a9786613854919 010 $a1-118-35817-1 010 $a1-118-35751-5 010 $a1-118-35819-8 035 $a(CKB)2550000000105052 035 $a(EBL)965078 035 $a(OCoLC)799766415 035 $a(SSID)ssj0000686912 035 $a(PQKBManifestationID)11426320 035 $a(PQKBTitleCode)TC0000686912 035 $a(PQKBWorkID)10735254 035 $a(PQKB)11567971 035 $a(MiAaPQ)EBC965078 035 $a(EXLCZ)992550000000105052 100 $a20131111d2012|||| u|| | 101 0 $aeng 181 $ctxt 182 $cc 183 $acr 200 10$aAmino Acid Metabolism$b[electronic resource] 205 $a3rd ed. 210 $aHoboken $cWiley$d2012 215 $a1 online resource (480 p.) 300 $aDescription based upon print version of record. 311 $a0-470-66151-8 327 $a1.4.1 Purine synthesis 1.4.1.1 Phosphoribosyl pyrophosphate (PRPP) synthetase; 1.4.1.2 PRPP amidotransferase; 1.4.2 Purine catabolism and salvage; 1.4.2.1 Adenosine deaminase deficiency - severe combined immune deficiency; 1.4.2.2 Gout and hyperuricaemia; 1.4.2.3 HGPRT deficiency - the Lesch-Nyhan syndrome; 1.4.3 Pyrimidine synthesis; 1.4.3.1 Orotic aciduria; 1.4.4 Pyrimidine catabolism and salvage; 1.5 Deamination of amino acids; 1.5.1 Amino acid oxidases; 1.5.2 Amine oxidases; 1.5.3 Glutamate and alanine dehydrogenases; 1.5.4 Non-oxidative deamination of amino acids 327 $a1.5.5 Glutaminase and asparaginase 1.6 Excretion of nitrogenous waste; 1.6.1 Uricotelic and purinotelic species; 1.6.2 Ureotelic species; 1.6.2.1 Urea synthesis; 1.6.2.2 Inborn errors of metabolism affecting the urea synthesis cycle; 1.6.2.3 Entero-hepatic circulation of urea; 1.6.2.4 Canavanine; 1.7 Other nitrogenous compounds in human urine; 1.7.1 Aminoacidurias; Further reading; 2: Nitrogen Balance and Protein Turnover - Protein and Amino Acids in Human Nutrition; 2.1 Nitrogen balance and protein requirements; 2.1.1 Protein digestion and absorption 327 $a2.1.2 Protein digestibility and unavailable amino acids in dietary proteins 2.1.3 Obligatory nitrogen losses; 2.1.4 Dynamic equilibrium and tissue protein turnover; 2.1.5 Tissue protein catabolism; 2.1.5.1 Lysosomal autophagy; 2.1.5.2 Ubiquitin and the proteasome; 2.1.5.3 Active site proteolysis of apo-enzymes; 2.1.6 Whole body protein turnover; 2.1.6.1 The constant infusion, labelled precursor method; 2.1.6.2 The constant infusion, labelled end product method; 2.1.6.3 Rates of whole-body protein turnover; 2.1.6.4 The catabolic drive and amino acid oxidation 327 $a2.1.6.5 The energy cost of protein turnover 330 $aAmino Acid Metabolism, 3rd Edition covers all aspects of the biochemistry and nutritional biochemistry of the amino acids. Starting with an overview of nitrogen fixation and the incorporation of inorganic nitrogen into amino acids, the book then details other major nitrogenous compounds in micro-organisms, plants and animals. Contents include a discussion of the catabolism of amino acids and other nitrogenous compounds in animals, and the microbiological reactions involved in release of nitrogen gas back into the atmosphere. Mammalian (mainly human) protein and amino acid 606 $aAmino acids$xMetabolism 606 $aAmino Acids, Peptides, and Proteins 606 $aMetabolic Phenomena 606 $aDrugs 606 $aMetabolism 606 $aAmino Acids 615 0$aAmino acids$xMetabolism 615 2$aAmino Acids, Peptides, and Proteins 615 2$aMetabolic Phenomena 615 2$aDrugs 615 2$aMetabolism 615 2$aAmino Acids 676 $a572.65 676 $a572/.65 700 $aBender$b David A$0321362 801 0$bAU-PeEL 801 1$bAU-PeEL 801 2$bAU-PeEL 906 $aBOOK 912 $a9910139693803321 996 $aAmino acid metabolism$9809162 997 $aUNINA