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010   $a1-283-45422-X
010   $a9786613454225
010   $a3-527-64482-2
010   $a3-527-64479-2
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035   $a(OCoLC)775871780
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035   $a(PQKBTitleCode)TC0000642007
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100   $a20120309d2012      uy             0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 00$aTherapeutic proteins$b[electronic resource] $estrategies to modulate their plasma half-lives /$fedited by Roland Kontermann
210   $aWeinheim, Germany $cWiley-Blackwell$d2012
215   $a1 online resource (374 p.)
300   $aDescription based upon print version of record.
311   $a3-527-32849-1 
320   $aIncludes bibliographical references and index.
327   $apt. 1. General information -- pt. 2. Half-life extension through chemical and post-translational modifications -- pt. 3. Half-life modulation involving recycling by the neonatal Fc receptor -- pt. 4. Half-life extension with pharmaceutical formulations.
330   $aFor this ready reference, the internationally renowned authority in the field, Roland Kontermann, has assembled a team of outstanding contributors from industry and academia to convey the worldwide knowledge on modifying therapeutic proteins in order to optimize their pharmacological potential. The result is a comprehensive work covering all approaches and aspects of the topic in one handy volume, making this indispensable reading for companies and research institutions working on the development of biopharmaceuticals.
606   $aProtein drugs$xDesign
606   $aProteins$xTherapeutic use
615  0$aProtein drugs$xDesign.
615  0$aProteins$xTherapeutic use.
676   $a615.3
701   $aKontermann$b Roland$0941977
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910139690003321
996   $aTherapeutic proteins$92125405
997   $aUNINA