LEADER 05578nam 2200709 a 450 001 9910139627003321 005 20230803074003.0 010 $a1-283-20376-6 010 $a9786613203762 010 $a1-118-00345-4 010 $a1-118-00346-2 010 $a1-118-00344-6 035 $a(CKB)2550000000041200 035 $a(EBL)697493 035 $a(OCoLC)746324251 035 $a(SSID)ssj0000521615 035 $a(PQKBManifestationID)11355401 035 $a(PQKBTitleCode)TC0000521615 035 $a(PQKBWorkID)10523721 035 $a(PQKB)10422449 035 $a(MiAaPQ)EBC697493 035 $a(Au-PeEL)EBL697493 035 $a(CaPaEBR)ebr10484898 035 $a(CaONFJC)MIL320376 035 $a(PPN)171951581 035 $a(EXLCZ)992550000000041200 100 $a20100921d2011 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt 182 $cc 183 $acr 200 00$aComprehensive chromatography in combination with mass spectrometry$b[electronic resource] /$fedited by Luigi Mondello 210 1$aHoboken, N.J. :$cWiley,$dc2011. 215 $a1 online resource (497 p.) 225 1 $aWiley-Interscience series on mass spectrometry 225 1 $aTHEi Wiley ebooks 300 $aDescription based upon print version of record. 311 $a0-470-43407-4 320 $aIncludes bibliographical references and index. 327 $aComprehensive Chromatography in Combination with Mass Spectrometry; Contents; Contributors; Preface; 1. Introduction; 1.1 Two-Dimensional Chromatography-Mass Spectrometry: A 50-Year-Old Combination; 1.2 Shortcomings of One-Dimensional Chromatography; 1.3 Benefits of Two-Dimensional Chromatography; 1.4 Book Content; 1.5 Final Considerations; 2. Multidimensional Gas Chromatography: Theoretical Considerations; 2.1 Symbols; 2.2 One-Dimensional GC; 2.3 Comprehensive GC x GC; 3. Multidimensional Liquid Chromatography: Theoretical Considerations; 3.1 Two-Dimensional LC Techniques 327 $a3.2 Peak Capacity in HPLC: One- and Multidimensional Separations 3.3 Orthogonality in Two-Dimensional LC-LC Systems; 3.4 Sample Dimensionality and Structural Correlations; 3.5 Separation Selectivity and Selection of Phase Systems in Two-Dimensional LC-LC; 3.6 Programmed Elution in Two-Dimensional HPLC; 3.7 Fraction Transfer Modulation in Comprehensive LC x LC: Additional Band Broadening; 3.8 Future Perspectives; 4. History, Evolution, and Optimization Aspects of Comprehensive Two-Dimensional Gas Chromatography; 4.1 Fundamentals of GC x GC; 4.2 Modulation; 4.3 GC x GC Data Interpretation 327 $a4.4 GC x GC Instrumentation 4.5 Thermal Modulators; 4.6 Comprehensive Two-Dimensional GC Method Optimization; 4.7 Final Remarks; 5. Flow-Modulated Comprehensive Two-Dimensional Gas Chromatography; 5.1 Timing Requirements of GC x GC Modulators; 5.2 Criteria for Evaluating Modulators; 5.3 Forms of Modulation; 5.4 Single-Stage Flow Modulation; 5.5 Two-Stage Flow Modulation; 5.6 Summary of Flow Modulators; 5.7 Brief Comparison to Thermal Modulation; 5.8 Concluding Remarks; 6. Comprehensive Two-Dimensional Gas Chromatography Combined with Mass Spectrometry 327 $a6.1 Instrument Requirements for GC x GC-MS 6.2 Data Processing of GC x GC-TOF MS Results; 6.3 Method Translation in GC x GC-MS; 6.4 GC x MS; 6.5 Conventional and Alternative Modulation Techniques for GC x GC-MS; 6.6 GC x GC-MS Applications; 6.7 Concluding Remarks; 7. Detector Technologies and Applications in Comprehensive Two-Dimensional Gas Chromatography; 7.1 Detection in GC x GC; 7.2 Comments on GC x GC with Mass Spectrometry; 7.3 Flame Ionization Detection in GC x GC; 7.4 Electron Capture Detection in GC x GC; 7.5 Sulfur Chemiluminescence Detection in GC x GC 327 $a7.6 Nitrogen Chemiluminescence Detection in GC x GC 7.7 Atomic Emission Detection in GC x GC; 7.8 Thermionic Detection in GC x GC; 7.9 Flame Photometric Detection in GC x GC; 7.10 Case Study of GC x GC with Selective Detection; 7.11 Dual Detection with GC x GC; 7.12 Conclusions; 8. History, Evolution, and Optimization Aspects of Comprehensive Two-Dimensional Liquid Chromatography; 8.1 Method Development and Instrumentation; 8.2 Technical Problems in Comprehensive Liquid Chromatography; 8.3 Detection; 8.4 Data Representation; 8.5 Instrumentation 327 $a8.6 Milestones in Comprehensive Liquid Chromatography 330 $aThis book provides a detailed description of various multidimensional chromatographic separation techniques. The editor first provides an introduction to the area and then dives right into the various complex separation techniques. While still not used routinely comprehensive chromatography techniques will help acquaint the readers with the fundamentals and possible benefits of multi-dimensional separations coupled with mass spectrometry. The topics include a wide range of material that will appease all interested in either entering the field of multidimensional chromatography and those look 410 0$aWiley-Interscience series on mass spectrometry. 410 0$aTHEi Wiley ebooks. 606 $aChromatographic analysis 606 $aMultidimensional chromatography 615 0$aChromatographic analysis. 615 0$aMultidimensional chromatography. 676 $a543/.8 701 $aMondello$b Luigi$0295088 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910139627003321 996 $aComprehensive chromatography in combination with mass spectrometry$92270345 997 $aUNINA