LEADER 03466oam 2200649 a 450 001 9910139598603321 005 20240129220431.0 010 $a1-283-23983-3 010 $a9786613239839 010 $a1-118-07563-3 010 $a1-118-07564-1 010 $a1-118-07562-5 035 $a(CKB)2550000000046033 035 $a(EBL)693238 035 $a(OCoLC)757395650 035 $a(SSID)ssj0000535002 035 $a(PQKBManifestationID)12215947 035 $a(PQKBTitleCode)TC0000535002 035 $a(PQKBWorkID)10536458 035 $a(PQKB)10021914 035 $a(MiAaPQ)EBC693238 035 $a(Au-PeEL)EBL693238 035 $a(CaPaEBR)ebr10494572 035 $a(CaONFJC)MIL323983 035 $a(EXLCZ)992550000000046033 100 $a20110201h20112011 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aChiral drugs $echemistry and biological action /$fedited by Guo-Qiang Lin, Qi-Dong You, Jie-Fei Cheng 210 1$aHoboken, N.J. :$cWiley,$d2011. 210 4$dİ2011 215 $a1 online resource (x, 456 pages) $cillustrations 300 $aDescription based upon print version of record. 311 0 $a0-470-58720-2 320 $aIncludes bibliographical references and index. 327 $aMachine generated contents note: Chapter 1. Overview of chirality and chiral drugs (Guo-Qiang Lin, Jiange Zhang and Jie-Fei Cheng). -- Chapter 2. Chiral drugs through asymmetric synthesis (Guo-Quiang Lin and Xing-Wen Sun). -- Chapter 3. Chiral drugs via biocatalytical approaches (Jianqiang Wang and Wenya Lu). -- Chapter 4. Chiral resolution (Qi-Dong You). -- Chapter 5. Fluorine-containing chiral drugs (Xiao-Long Qiu, Xuyi Yue and Feng-Ling Qing). -- Chapter 6. Industrial application of chiral technologies (Hui-Ying (Harry) Li, Rui Liu, Carl Behrens, and Chao-Ying Ni). -- Chapter 7. Computation modeling study on mechanism-of-action of chiral drugs (Deping Wang and Eric Gu). -- Chapter 8. Pharmacology of chiral drugs (Yongge Liu and Xiao-Hui Gu). -- Chapter 9. Pharmacokinetics of chiral drugs (Hanqing Dong, Xiaochuan Guo and Zengbiao Li). -- Chapter 10. Toxicology of chiral drugs (Guang Yang and Hai-Zhi Bu). -- Chapter 11. Representative chiral drugs (Jiangqin Sun, Dingguo Liu and Zhimin Wang). 330 $a"This book overviews chiral drugs and their impact in the pharmaceutical industry. The chapters detail basics and trends in chiral drug discovery and development, as well as techniques / skills and trends of asymmetric synthesis. The first section introduces the general concept of chirality and its impact on the drug discovery and development. This part includes history of chiral drug development, key technologies for preparation of chiral drugs, and industrial applications of chiral technologies"--Provided by publisher. 606 $aChiral drugs 606 $aDrug development 606 $aStructure-activity relationships (Biochemistry) 615 0$aChiral drugs. 615 0$aDrug development. 615 0$aStructure-activity relationships (Biochemistry) 676 $a615/.19 701 $aLin$b Guo-Qiang$f1943-$066570 701 $aYou$b Qi-Dong$0898249 701 $aCheng$b Jie-Fei$0898250 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910139598603321 996 $aChiral drugs$92007072 997 $aUNINA