LEADER 05423nam 2200673 450 001 9910139423703321 005 20170924194545.0 010 $a1-283-37042-5 010 $a9786613370426 010 $a3-527-63137-2 010 $a3-527-63136-4 035 $a(CKB)2480000000008464 035 $a(EBL)700845 035 $a(OCoLC)818852869 035 $a(SSID)ssj0000403430 035 $a(PQKBManifestationID)11276788 035 $a(PQKBTitleCode)TC0000403430 035 $a(PQKBWorkID)10433072 035 $a(PQKB)10200684 035 $a(MiAaPQ)EBC700845 035 $a(EXLCZ)992480000000008464 100 $a20160816h20082008 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aMembranes for life sciences$hVolume 1 /$fedited by Klaus-Viktor Peinemann and Suzana Pereira Nunes 210 1$aWeinheim, Germany :$cWiley-VCH,$d2008. 210 4$d?2008 215 $a1 online resource (346 p.) 225 1 $aMembranes 300 $aDescription based upon print version of record. 311 $a3-527-31480-6 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aMembranes for the Life Sciences Volume- 1; Contents; Preface; Contributors ((Peinemann Vol. 1)); 1 Membranes in Hemodialysis; 1.1 Introduction; 1.2 Historical Achievements; 1.3 Membranes for Hemodialysis: Polymers and Nomenclature; 1.3.1 Membranes from Regenerated Cellulose; 1.3.1.1 Modified Cellulosic Membranes; 1.3.1.2 Cellulose Acetates; 1.3.1.3 DEAE-Modified Cellulose, Hemophan; 1.3.1.4 Benzyl-Modified Cellulose (Synthetically Modified Cellulose, SMC); 1.3.1.5 PEG-Grafted Cellulose; 1.3.1.6 Vitamin E-Modified Cellulosic Membranes; 1.3.2 Synthetic Membranes; 1.3.2.1 Polyacrylonitrile (PAN) 327 $a1.3.2.2 Polymethylmethacrylate (PMMA)1.3.2.3 Polysulfone (PSu); 1.3.2.4 Polyamide (PA); 1.4 Dialyzer Constructions; 1.4.1 Hollow Fiber Dialyzers; 1.4.2 Housing; 1.4.3 Potting Material; 1.4.4 Fiber Bundle; 1.5 Dialysis Membranes and Performance: Principles of Membrane Transport; 1.6 Dialysis Membranes and Biocompatibility; 1.6.1 Some Basic Information on Membranes and Biocompatibility Parameters; 1.6.2 Thrombogenicity of Different Types of Dialyzers and Filters; 1.6.3 Complement Activation by Different Dialyzers and Filters; 1.6.4 Cell Activation by Different Types of Dialyzers and Hemofilters 327 $a1.6.4.1 Apoptosis1.6.5 Oxygen Species Production - Induction of Oxidative Stress; 1.6.5.1 Degranulation of Neutrophils; 1.6.6 Stimulation of Cytokine Generation by Different Types of Dialyzers and Hemofilters; 1.6.6.1 The Impact of Membrane Types on LPS-Stimulated IL-1? Secretion; 1.6.7 The Impact of Large-Pore Dialysis Membranes on the Inflammatory Response in HD Patients by Cytokine Elimination; 1.6.8 The Effect of Different Dialyzers on the Acute Phase Reaction; 1.6.9 Activation of the Kinin System by Different Types of Dialyzers and Hemofilters; 1.7 Conclusion 327 $a2 Membranes for Artificial Lungs2.1 Introduction; 2.2 History of Blood Oxygenation; 2.2.1 Membrane Oxygenators; 2.3 Principle of Gas Transfer; 2.4 Membranes and Membrane Properties; 2.4.1 Microporous Membranes; 2.4.2 Dense Membranes/''Diffusion Membranes''; 2.5 Membrane Production; 2.6 Operational Modes and Membrane Makeup in Oxygenators; 2.6.1 Microporous Capillary Membranes, Blood Inside; 2.6.2 Microporous Capillary Membranes, Blood Outside; 2.7 Extracorporeal Circulation; 2.7.1 Cardiodiapulmonary Bypass (CPB); 2.7.2 Lung Support Systems; 3 Membranes for Blood Fractionation/Apheresis 327 $a3.1 Introduction3.2 History of Plasmapheresis; 3.3 Principles of Plasmapheresis; 3.4 Membranes and Membrane Properties; 3.4.1 Plasma Separation Membranes; 3.4.2 Plasma Fractionation Membranes; 3.5 Membrane Production; 3.6 Operational Modes in Plasmapheresis Procedures; 3.7 Medical Indications for Blood Plasma Treatment; 4 Membranes in the Biopharmaceutical Industry; 4.1 Introduction; 4.2 Microfiltration Membranes Used in the Biotech Industry; 4.2.1 Introduction; 4.2.2 Microfiltration Membranes: Development of Industrial Membranes; 4.2.3 Effect of Membrane Structure on Properties 327 $a4.2.4 Aspects of Cartridge Design 330 $aExamining artificial membranes in terms of biocompatibility, drug delivery and controlled release, this book illustrates how existing membrane technologies are being exploited and advanced in emerging medical applications. This work, edited by internationally recognized experts, has author contributions from prominent members of this field who discuss details of all aspects of this technology. This volume provides broad, yet detailed information on synthetic membranes and their applications, including dialysis and artificial kidneys, gas exchange, artificial lungs, devices to assist liver func 410 0$aMembranes 606 $aMembranes (Technology) 606 $aLife sciences 608 $aElectronic books. 615 0$aMembranes (Technology) 615 0$aLife sciences. 676 $a570.28 676 $a660.28424 702 $aPeinemann$b K. V$g(Klaus-Viktor), 702 $aNunes$b S. P$g(Suzana Pereira), 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910139423703321 996 $aMembranes for life sciences$91911260 997 $aUNINA