LEADER 05547nam 2200697Ia 450 001 9910139396903321 005 20230725041457.0 010 $a1-118-09954-0 010 $a1-283-02501-9 010 $a9786613025012 010 $a0-470-87238-1 010 $a0-470-87239-X 035 $a(CKB)2480000000008388 035 $a(EBL)698872 035 $a(OCoLC)689995803 035 $a(SSID)ssj0000517370 035 $a(PQKBManifestationID)11365825 035 $a(PQKBTitleCode)TC0000517370 035 $a(PQKBWorkID)10486924 035 $a(PQKB)11002403 035 $a(MiAaPQ)EBC698872 035 $a(Au-PeEL)EBL698872 035 $a(CaPaEBR)ebr10447795 035 $a(CaONFJC)MIL302501 035 $a(EXLCZ)992480000000008388 100 $a20100622d2011 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aCalcium binding proteins$b[electronic resource] /$fEugene A. Permyakov, Robert H. Kretsinger 210 $aHoboken, NJ $cJohn Wiley & Sons$dc2011 215 $a1 online resource (600 p.) 225 0$aWiley series in protein and peptide science 300 $aDescription based upon print version of record. 311 $a0-470-52584-3 320 $aIncludes bibliographical references (p. 459-565) and index. 327 $aCALCIUM BINDING PROTEINS; CONTENTS; Preface; 1 Historical Perspective; 1.1 Biomineralization; 1.2 Coagulation; 1.3 Secondary Messengers (Anticipated); 1.4 Colloids; 1.5 Cross-Linking and Cell Surfaces; 1.6 Secondary Messengers (Updated); 1.7 Pumps, Channels, and Ionophores; 1.8 Calcium Binding Proteins; 1.9 Secondary Messengers (Yet Again); 1.10 Mitochondria; 1.11 Pumps, Channels, and Ionophores; 1.12 Hormones; 1.13 Measurement; 1.14 Biomineralization: Redux; 2 Physiological Processes Involving Calcium Binding Proteins; 2.1 Calcium as a Secondary Messenger; 2.2 Calcium Buffers 327 $a2.3 Calcium Pumps and Channels2.4 Mitochondria; 2.5 Eubacteria; 2.6 Calcium and Extracellular Proteins; 2.7 Biomineralization; 2.8 Calcium and Viruses; 3 Comparison of the Ca2+ Ion with Other Metal Cations; 3.1 Calcium Isotopes; 3.2 Calcium in the Environment; 3.3 Uses of Calcium; 3.4 Health Effects of Calcium; 3.5 Biologically Significant Metals in the Periodic Table; 3.6 Hydration of Metal Ions; 3.7 "Hard" and "Soft" Metal Ions; 4 Complexes of Calcium and Other Cations with Compounds of Low Molecular Weight; 4.1 Crystal Structures of Complexes of Calcium with Low Molecular Weight Compounds 327 $a4.2 Dissociation Constants of Calcium and Analogs with Small Compounds4.3 Solubilities of Calcium and Analogs with Small Compounds; 5 Stoichiometry, Kinetics, and Thermodynamics of Calcium Binding; 5.1 Stoichiometry, Affinity, and Cooperativity of Binding; 5.2 Kinetics of Binding; 5.3 Partition of Free Energy of Binding (G) Among Enthalpy (H) and Entropy (S); 6 Experimental Methods Used to Study Calcium Binding to Proteins; 6.1 Radioactivity; 6.2 Ion-Selective Electrodes; 6.3 Calcium Buffers; 6.4 Dialysis, Equilibrium, and Flow; 6.5 Proteolysis; 6.6 Deuterium Exchange 327 $a6.7 Isothermal Titration Calorimetry6.8 Differential Scanning Calorimetry; 6.9 Mass Spectroscopy; 6.10 Calcium-Specific Dyes and Fluors; 6.11 Atomic Flame Absorption Spectroscopy; 6.12 Absorption Spectroscopy; 6.13 Fluorescence Spectroscopy; 6.14 Circular Dichroic and Optical Rotatory Dispersion Spectroscopy; 6.15 Nuclear Magnetic Resonance; 6.16 Electron Spin Resonance; 6.17 Surface Plasmon Resonance; 6.18 Extended X-ray Absorption Spectroscopy; 6.19 Small Angle X-ray Scattering; 6.20 Crystallography; 7 Structure and Evolution of Proteins; 7.1 Domain; 7.2 Structure; 7.3 Evolution 327 $a8 Protein Complexes with Metals Other than Calcium8.1 Essential Hard Cations; 8.2 Essential Metals with Several Valence States; 8.3 Conclusions; 9 Nonessential Metals; 9.1 Alkali Metals (Group Ia); 9.2 Alkali Earth Metals (Group IIa); 9.3 Group IIIa; 9.4 Group IVa; 9.5 Group Va; 9.6 Group VIIa; 9.7 Group VIII; 9.8 Group Ib; 9.9 Mercury (Group IIb); 9.10 Group IIIb; 9.11 Group IVb; 9.12 Group Vb; 9.13 Polonium (Group VIb); 9.14 Conclusions and Generalizations; 10 Parvalbumin; 10.1 Structure; 10.2 Function; 11 EF-Hand Proteins 327 $a11.1 CTER (Calmodulin, Troponin C, Essential and Regulatory Light Chain) Subfamily 330 $aCalcium Binding Proteins explains the unique and highly diverse functions of calcium in biology, which are realized by calcium binding proteins. The structures and physical characteristics of these calcium binding proteins are described, as well as their functions and general patterns of their evolution. Techniques that underlie the description of proteins are discussed, including NMR, circular dichroism, optical rotatory dispersion spectroscopy, calorimetry,and crystallography. The book discusses the patterns of bochmical phenomena such as calcium homeostasis, mineralization, and cell 410 0$aWiley Series in Protein and Peptide Science 606 $aCalcium-binding proteins 606 $aCalcium in the body 615 0$aCalcium-binding proteins. 615 0$aCalcium in the body. 676 $a572.69 676 $a572/.69 700 $aPermi?akov$b E. A$g(Evgenii? Anatol?evich)$0922345 701 $aKretsinger$b Robert H$0922346 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910139396903321 996 $aCalcium binding proteins$92069627 997 $aUNINA