LEADER 05291nam 2200637Ia 450 001 9910139391303321 005 20200520144314.0 010 $a0-470-97667-5 010 $a1-280-75173-8 010 $a9786613677853 010 $a0-470-97661-6 010 $a0-470-97662-4 035 $a(CKB)2480000000008405 035 $a(EBL)645012 035 $a(OCoLC)695561404 035 $a(SSID)ssj0000470944 035 $a(PQKBManifestationID)12211421 035 $a(PQKBTitleCode)TC0000470944 035 $a(PQKBWorkID)10416871 035 $a(PQKB)11521612 035 $a(MiAaPQ)EBC645012 035 $a(EXLCZ)992480000000008405 100 $a20100903d2011 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aLipids and essential oils as antimicrobial agents /$feditor, Halldor Thormar 210 $aChichester, West Sussex $cJ. Wiley$d2011 215 $a1 online resource (338 p.) 300 $aDescription based upon print version of record. 311 $a0-470-74178-3 320 $aIncludes bibliographical references and index. 327 $aLipids and Essential Oils asAntimicrobial Agents; Contents; List of Contributors; Introduction; 1 Membranes as Targets of Antimicrobial Lipids; 1.1 Introduction; 1.2 Oil and Water Don't Mix!; 1.3 Polar Lipids; 1.3.1 The Amphiphilic Character of Polar Lipids; 1.3.2 Hydrophobic Constituents of Lipids; 1.3.3 Polar Groups of Complex Lipids; 1.4 Properties of Surfactants; 1.4.1 Critical Micelle Concentration; 1.4.2 Aggregation of Surface-Active Molecules; 1.4.3 The Influence of Solvent; 1.5 Cell Membranes; 1.5.1 Membrane Lipids; 1.5.2 Lipid Domains in Membranes; 1.5.3 Membrane Proteins 327 $a1.5.4 Membrane Stability1.5.4.1 Membrane Lipid Phase Behaviour; 1.5.4.2 Membrane Lipid Homeostasis in Homoiothermic Organisms; 1.5.4.3 Membrane Lipid Adaption in Poikilothermic Organisms; 1.6 The Action of Antimicrobial Lipids on Cell Membranes; 1.7 Conclusions; Acknowledgements; References; 2 Antibacterial Effects of Lipids: Historical Review (1881 to 1960); 2.1 Introduction; 2.2 Antibacterial Activity of Soaps; 2.2.1 Antibacterial Action of Fatty Acids and Their Derivatives; 2.3 Inhibition of Lipids and Serum Albumin against the Antibacterial Action of Soaps 327 $a2.4 Diverse Actions of Fatty Acids and Their Salts on Bacteria2.5 The Nature of the Bactericidal Action of Fatty Acids; 2.6 A Possible Role of Soaps and Fatty Acids in Host Defence against Bacteria; 2.7 Studies of Prophylactic and Therapeutic Applications of Soaps and Fatty Acids; 2.8 Conclusions; References; 3 Antibacterial, Antiviral and Antifungal Activities of Lipids; 3.1 Introduction; 3.2 Antibacterial Activities of Fatty Acids and Monoglycerides; 3.2.1 Activities against Gram-Positive Bacteria In Vitro; 3.2.2 Activities against Gram-Negative Bacteria In Vitro 327 $a3.2.3 Antibacterial Mechanism3.2.4 A Possible Role of Antimicrobial Lipids in Host Defence against Bacteria; 3.3 Antiviral Activities of Fatty Alcohols, Fatty Acids and Monoglycerides; 3.3.1 Early Studies of Antiviral Lipids; 3.3.2 Antiviral Activities of Milk Lipids; 3.3.3 Antiviral Activities of Lipids and Fatty Alcohols; 3.3.4 Antiviral Mechanism of Lipids; 3.4 Antifungal Activities of Fatty Acids and Monoglycerides; 3.4.1 In Vitro Studies; 3.4.2 In Vivo Studies; 3.5 Conclusions; References; 4 Antimicrobial Lipids in Milk; 4.1 Introduction; 4.2 Occurrence; 4.2.1 Biosynthesis 327 $a4.2.2 Quantitative Assays4.2.2.1 Measurement of Antibacterial Activity; 4.2.2.2 Measurement of Antiviral Activity; 4.3 Molecular Properties; 4.3.1 Lipids in Milk and Plant Oils; 4.3.2 Dependence of Antimicrobial Activity on Chain Length, Saturation and pH; 4.4 Antimicrobial Activity; 4.4.1 Mechanism of Action; 4.4.2 Synergy between Antimicrobial Lipids and Antimicrobial Peptides; 4.4.2.1 Antimicrobial Peptides and Proteins; 4.4.2.2 Potential Synergism between Antimicrobial Milk Lipids and Peptides; 4.4.3 Influencing Factors; 4.4.4 Spectrum; 4.5 Applications 327 $a4.5.1 Additive Advantage to Foods and Biological Products 330 $aLipids and essential oils have strong antimicrobial properties - they kill or inhibit the growth of microbes such as bacteria, fungi, or viruses. They are being studied for use in the prevention and treatment of infections, as potential disinfectants, and for their preservative and antimicrobial properties when formulated as pharmaceuticals, in food products, and in cosmetics. Lipids and Essential Oils as Antimicrobial Agents is a comprehensive review of the scientific knowledge in this field. International experts provide summaries on: the chemical and biologi 606 $aAnti-infective agents 606 $aEssences and essential oils$xTherapeutic use 606 $aLipids$xTherapeutic use 615 0$aAnti-infective agents. 615 0$aEssences and essential oils$xTherapeutic use. 615 0$aLipids$xTherapeutic use. 676 $a615/.792 701 $aThormar$b Halldor$0944704 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910139391303321 996 $aLipids and essential oils as antimicrobial agents$92132592 997 $aUNINA