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100   $a20100629d2010      uy             0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 04$aThe chemical biology of DNA damage$b[electronic resource] /$fedited by Nicholas E. Geacintov and Suse Broyde
205   $a1st ed.
210   $aWeinheim [Germany] $cWiley$d2010
215   $a1 online resource (473 p.)
300   $aDescription based upon print version of record.
311   $a3-527-32295-7 
320   $aIncludes bibliographical references and index.
327   $apt. 1. Chemistry and biology of DNA lesions -- pt. 2 New frontiers and challenges  : understanding structure-function relationships and biological activity.
330   $aBringing the power of biochemical analysis to toxicology, this modern reference explains genotoxicity at the molecular level, showing the links between a DNA lesion and the resulting cellular or organismic response. Clearly divided into two main sections, Part 1 focuses on selected examples of important DNA lesions and their biological impact, while the second part covers current advances in assessing and predicting the genotoxic effects of chemicals, taking into account the biological responses mediated by the DNA repair, replication and transcription machineries.A ready reference for bio
606   $aDNA damage
615  0$aDNA damage.
676   $a572.8
676   $a572.86 22
701   $aGeacintov$b Nicholas E$0995121
701   $aBroyde$b Suse$0995122
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910139197403321
996   $aThe chemical biology of DNA damage$92279449
997   $aUNINA