LEADER 05450nam 22006971 450 001 9910138994003321 005 20230803220324.0 010 $a1-118-73881-0 010 $a1-118-73891-8 035 $a(CKB)2550000001138461 035 $a(EBL)1504471 035 $a(OCoLC)862049808 035 $a(SSID)ssj0001039368 035 $a(PQKBManifestationID)11668227 035 $a(PQKBTitleCode)TC0001039368 035 $a(PQKBWorkID)10990331 035 $a(PQKB)10368840 035 $a(MiAaPQ)EBC1504471 035 $a(Au-PeEL)EBL1504471 035 $a(CaPaEBR)ebr10795320 035 $a(CaONFJC)MIL538162 035 $a(EXLCZ)992550000001138461 100 $a20131031d2014 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aVeterinary allergy /$fedited by Chiara Noli, Aiden P. Foster, Wayne Rosenskrantz 210 1$aChichester, West Sussex ;$aHoboken, New Jersey :$cWiley Blackwell,$d2014. 215 $a1 online resource (472 p.) 300 $aDescription based upon print version of record. 311 $a0-470-67241-2 311 $a1-306-06911-4 320 $aIncludes bibliographical references and index. 327 $aCover; Title page; Copyright page; Contents; Acknowledgments; Contributors; Foreword; Introduction: the immunological basis of allergic diseases; Part 1: Canine Allergy; Section 1: Canine Atopic Dermatitis; 1: Introduction: canine atopic dermatitis as an evolving, multifactorial disease; References; 2: Canine immunoglobulin E; Introduction; The role of immunoglobulin E in atopic disease; Immunoglobulin E interaction with immune and inflammatory cells; The immunoglobulin E network of soluble receptors and autoantibody complexes; Therapeutic anti-immunoglobulin E; Conclusion; References 327 $a3: The aberrant immune system in atopic dermatitisAtopic dermatitis as a type I hypersensitivity: the role of mast cells, histamine, IgE, and leukotrienes; The role of dendritic cells; T cells: different populations and cytokine response; T regulatory cells or Tregs; Keratinocytes: an active player in the immune response; Summary of proposed pathogenesis; References; 4: Allergens and environmental influence; Introduction; Sources of allergens; House dust and storage mites; Human, feline, canine, equine, and other dandruffs; Feathers; Cockroach; Pollens; Mould spores 327 $aEnvironment and canine atopic dermatitisMites as triggers of canine atopic dermatitis flares and route of sensitization; Environmental allergen avoidance as a therapeutic tool; Choosing environmental allergens for allergen-specific immunotherapy (ASIT); Allergen specificities; Major and minor allergens; Panallergens; Non-allergenic mode of action; Conclusion; Internet sites; References; 5: The genetics of canine atopic dermatitis; Introduction; Investigating atopic dermatitis-associated genotypes; Genome-wide linkage studies; Candidate gene association studies; Genome-wide association studies 327 $aQuantitative reverse transcription polymerase chain reaction (RT-PCR)Bias and false results; Genomic studies in canine atopic dermatitis; Canine atopic dermatitis is a complex disease; Microarray studies; Candidate gene studies; Genome-wide linkage studies; Genome-wide association studies; Conclusion; References; 6: Skin barrier and its role in the pathophysiology of atopic dermatitis; Introduction; Methods to determine impairment of barrier function of the canine skin; Extracellular lipids in the stratum corneum and atopic dermatitis 327 $aStructure and metabolic pathway of ceramides in the epidermisReduction of ceramides in the stratum corneum in dogs with atopic dermatitis; Current evidence for aberrant filaggrin expression in dogs with atopic dermatitis; Structure and function of filaggrin in the epidermis and its role in humans and mice; Aberrant expression of filaggrin in canine atopic dermatitis-what we know so far; Other barrier abnormalities in human atopic dermatitis; Future perspectives for the investigation of cutaneous barrier function in canine atopic dermatitis; References 327 $a7: The role of bacterial agents in the pathogenesis of canine atopic dermatitis 330 $a The current state of knowledge on this increasingly important subject is beautifully described in this, the first truly comprehensive text of allergic diseases affecting the major veterinary species. It will be an invaluable guide to students, clinicians and researchers alike. From the Foreword by Professor Richard Halliwell, MS, PhD, VetMB, MRCVS, Dip ACVD Veterinary Allergy is the first comprehensive, high quality reference dealing with all aspects of veterinary allergy in all species and all body systems involved with allergy. Providing solid breadth and excellent dep 606 $aAllergy in animals 606 $aAllergy in cats 606 $aAllergy in dogs 606 $aVeterinary medicine 615 0$aAllergy in animals. 615 0$aAllergy in cats. 615 0$aAllergy in dogs. 615 0$aVeterinary medicine. 676 $a636.089697 701 $aFoster$b Aiden P$0870673 701 $aNoli$b Chiara$0506401 701 $aRosenkrantz$b Wayne$0870674 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910138994003321 996 $aVeterinary allergy$91943667 997 $aUNINA