LEADER 05745nam 22008293u 450 001 9910137629503321 005 20230803032555.0 010 $a3-527-64411-3 035 $a(CKB)3190000000022655 035 $a(EBL)1422497 035 $a(SSID)ssj0000667290 035 $a(PQKBManifestationID)11378771 035 $a(PQKBTitleCode)TC0000667290 035 $a(PQKBWorkID)10674742 035 $a(PQKB)10746160 035 $a(MiAaPQ)EBC1422497 035 $a(EXLCZ)993190000000022655 100 $a20131104d2013|||| u|| | 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aBioelectrochemistry$b[electronic resource] $eFundamentals, Applications and Recent Developments 210 $aHoboken $cWiley$d2013 215 $a1 online resource (413 p.) 225 1 $aAdvances in Electrochemical Science and Engineering ;$vv. 13 300 $aDescription based upon print version of record. 311 $a3-527-32885-8 327 $aAdvances in Electrochemical Science and Engineering, Volume 13; Contents; Preface; List of Contributors; 1: Amperometric Biosensors; 1.1 Introduction; 1.1.1 Definition of the Term "Biosensor"; 1.1.2 Milestones and Achievements Relevant to Biosensor Research and Development; 1.1.3 "First-Generation" Biosensors; 1.1.4 "Second-Generation" Biosensors; 1.1.5 "Third-Generation" Biosensors; 1.1.6 Reagentless Biosensor Architectures; 1.1.7 Parameters with a Major Impact on Overall Biosensor Response; 1.1.8 Application Areas of Biosensors; 1.2 Criteria for "Good" Biosensor Research 327 $a1.3 Defining a Standard for Characterizing Biosensor Performances1.4 Success Stories in Biosensor Research; 1.4.1 Direct ET Employed for Biosensors and Biofuel Cells; 1.4.2 Direct ET with Glucose Oxidase; 1.4.3 Mediated ET Employed for Biosensors and Biofuel Cells; 1.4.4 Nanomaterials and Biosensors; 1.4.4.1 Modification of Macroscopic Transducers with Nanomaterials; 1.4.4.2 Nanometric Transducers; 1.4.4.3 Modification of Biomolecules with Nanomaterials; 1.4.5 Implanted Biosensors for Medical Research and Health Check Applications 327 $a1.4.6 Nucleic Acid-Based Biosensors: Nucleic Acid Chips, Arrays, and Microarrays1.4.7 Immunosensors; 1.4.7.1 Labeled Approaches; 1.4.7.2 Nonlabeled Approaches; 1.5 Conclusion; Acknowledgments; Abbreviations; Glossary; References; 2: Imaging of Single Biomolecules by Scanning Tunneling Microscopy; 2.1 Introduction; 2.2 Interfacial Electron Transfer in Molecular and Protein Film Voltammetry; 2.2.1Theoretical Notions of Interfacial Chemical and Bioelectrochemical Electron Transfer; 2.2.2 Nuclear Reorganization Free Energy 327 $a2.2.3 Electronic Tunneling Factor in Long-Range Interfacial (Bio)electrochemical Electron Transfer2.3 Theoretical Notions in Bioelectrochemistry towards the Single-Molecule Level; 2.3.1 Biomolecules in Nanoscale Electrochemical Environment; 2.3.2 Theoretical Frameworks and Interfacial Electron Transfer Phenomena; 2.3.2.1 Redox (Bio)molecules in Electrochemical STM and Other Nanogap Configurations; 2.3.2.2 New Interfacial (Bio)electrochemical Electron Transfer Phenomena 327 $a2.4 In Situ Imaging of Bio-related Molecules and Linker Molecules for Protein Voltammetry with Single-Molecule and Sub-molecular Resolution2.4.1 Imaging of Nucleobases and Electronic Conductivity of Short Oligonucleotides; 2.4.2 Functionalized Alkanethiols and the Amino Acids Cysteine and Homocysteine; 2.4.2.1 Functionalized Alkanethiols as Linkers in Metalloprotein Film Voltammetry; 2.4.2.2 In Situ STM of Cysteine and Homocysteine; 2.4.2.3 Theoretical Computations and STM Image Simulations; 2.4.3 Single-Molecule Imaging of Bio-related Small Redox Molecules 327 $a2.5 Imaging of Intermediate-Size Biological Structures: Lipid Membranes and Insulin 330 $aBioelectrochemistry is a fast growing field at the interface between electrochemistry and other sciences such as biochemistry, analytical chemistry and medicinal chemistry. In the recent years, the methods and the understanding of the fundamentals have seen significant progress, which has led to rapid development in the field.Here, the expert editors have carefully selected contributions to best reflect the latest developments in this hot and rapidly growing interdisciplinary topic. The resulting excellent and timely overview of this multifaceted field covers recent methodological adva 410 0$aAdvances in Electrochemical Science and Engineering ;$vv. 13 606 $aBioelectric energy sources 606 $aBioelectrochemistry 606 $aEnergy metabolism -- Physiology 606 $aHuman Anatomy & Physiology$2HILCC 606 $aHealth & Biological Sciences$2HILCC 606 $aAnimal Biochemistry$2HILCC 615 4$aBioelectric energy sources. 615 4$aBioelectrochemistry. 615 4$aEnergy metabolism -- Physiology. 615 7$aHuman Anatomy & Physiology 615 7$aHealth & Biological Sciences 615 7$aAnimal Biochemistry 676 $a541.3 676 $a541.37 686 $aCHE 140f$2stub 686 $aCHE 802f$2stub 686 $aVE 6300.3$2rvk 686 $aVE 6350$2rvk 686 $aVN 6050$2rvk 686 $aWD 2600$2rvk 686 $aCHE802f$2stub 686 $aVE6300.3$2rvk 686 $aVE6350$2rvk 686 $aVN6050$2rvk 700 $aAlkire$b Richard C$0969181 701 $aKolb$b Dieter M$0884241 701 $aLipkowski$b Jacek$0993847 701 $aRoss$b Phil N$0996591 801 0$bAU-PeEL 801 1$bAU-PeEL 801 2$bAU-PeEL 906 $aBOOK 912 $a9910137629503321 996 $aBioelectrochemistry$92284972 997 $aUNINA