LEADER 01682nam 2200373Ia 450 001 996385874203316 005 20200824132154.0 035 $a(CKB)4940000000075935 035 $a(EEBO)2240955112 035 $a(OCoLC)ocm12256054e 035 $a(OCoLC)12256054 035 $a(EXLCZ)994940000000075935 100 $a19850711d1644 uy | 101 0 $aeng 135 $aurbn||||a|bb| 200 14$aThe merchant distressed his observations when he was a prisoner for debt in London in the yeare of our Lord 1637$b[electronic resource] $ein which the reader may take notice of I. his observations of many passages in the prison ... II. the severall humours and conditions of his fellow prisoners and others, III. his advice to them ... IV. Gods singular care and providence over all distressed prisoners and others who put their trust in him ... /$fwritten in plane verse by William Bagwell 210 $aLondon $cPrinted by T.H. for F.E. and are to be sold at his shop ...$d1644 215 $a[16], 119 p. $cport 300 $aReproduction of original in Huntington Library. 300 $aImperfect: engraved portrait lacking on film. 330 $aeebo-0113 606 $aPrisoners$zEngland$vEarly works to 1800 606 $aDebt, Imprisonment for$zGreat Britain 615 0$aPrisoners 615 0$aDebt, Imprisonment for 700 $aW. B$g(William Bagwell),$fb. 1593?$01002908 801 0$bEAA 801 1$bEAA 801 2$bm/c 801 2$bWaOLN 906 $aBOOK 912 $a996385874203316 996 $aThe merchant distressed his observations when he was a prisoner for debt in London in the yeare of our Lord 1637$92321189 997 $aUNISA LEADER 03993nam 2200565 450 001 9910137532003321 005 20230621140726.0 010 $a9782889195633 (ebook) 035 $a(CKB)3710000000569670 035 $a(SSID)ssj0001666204 035 $a(PQKBManifestationID)16455520 035 $a(PQKBTitleCode)TC0001666204 035 $a(PQKBWorkID)15000739 035 $a(PQKB)10802969 035 $a(WaSeSS)IndRDA00056079 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/42186 035 $a(EXLCZ)993710000000569670 100 $a20160829d2015 uy | 101 0 $aeng 135 $aur||||||||||| 181 $ctxt 182 $cc 183 $acr 200 00$aBiofilm formation by staphylococci and streptococci$b[electronic resource] $estructural, functional and regulatory aspects and implications for pathogenesis /$fedited by Joan A. Geoghegan and Pietro Speziale 210 $cFrontiers Media SA$d2015 210 31$aFrance :$cFrontiers Media SA,$d2015 215 $a1 online resource (111 pages) $cillustrations 225 0 $aFrontiers Research Topics,$x1664-8714 300 $aBibliographic Level Mode of Issuance: Monograph 320 $aIncludes bibliographical references. 330 $aMembers of the genus Staphylococcus and Streptococcus are the causative agnets of many human and animal diseases. Over the past decade the complete sequencing of many staphylococcal and streptococcal genomes has promoted a significant advance in our knowledge of these important pathogens. The pathogenicity of these bacteria is due to the expression of a large variety of virulence factors. Such determinants, which are cell wall-associated and secreted proteins, include adhesins that confer to the pathogen the ability to attach to extracellular matrix/plasma and host cell surfaces, proteins that contribute to host cell invasion and intracellular survival and soluble factors that decrease phagocytosis and modulate the immune response. Furthermore, these Gram-positive cocci in many natural environments (heart valve, lung, oral cavity, throat) and infections on implanted devices live in matrix-encased groups known as biofilms. Biofilms are specialized bacterial communities with high order organization analogous to that of a tissue in multicellular organism that adhere to abiotic or biological substrata and produce an exopolymeric matrix composed of polysaccarides, proteins, DNA or combination thereof. Bacteria within a biofilm persist in adverse conditions, show resistance to killing by antibiotics and to host immune defences and are difficult to eradicate and treat clinically. Therefore, understanding the mechanisms of biofilm development will allow us to effectively combat staphylococcal/streptococcal biofilm-based infections. This Research Topic will focus on the molecular components involved in biofilm formation by staphylococci and streptococci, the role they play in the development, maturation and dispersal of biofilm and on the regulatory aspects of such complex processes. The implication for the pathogenesis of infective diseases and potential therapeutic strategies against biofilm-based infections will be also discussed. The articles will highlight both the recent advances and future challenges inherent in this rapidly evolving area. 606 $aMicrobiology & Immunology$2HILCC 606 $aBiology$2HILCC 606 $aHealth & Biological Sciences$2HILCC 610 $aStreptococcus 610 $aPathogenesis 610 $acolonization 610 $aBiofilm 610 $aStaphylococcus 615 7$aMicrobiology & Immunology 615 7$aBiology 615 7$aHealth & Biological Sciences 700 $aPietro Speziale$4auth$01365330 702 $aGeoghegan$b Joan A 702 $aSpeziale$b Pietro 801 0$bPQKB 801 2$bUkMaJRU 912 $a9910137532003321 996 $aBiofilm formation by staphylococci and streptococci$93387034 997 $aUNINA LEADER 00777oas 2200289z- 450 001 9910473642303321 005 20210727085119.0 011 $a2747-5093 035 $a(CKB)5590000000469492 035 $a(DE-599)ZDB3053610-8 035 $a(EXLCZ)995590000000469492 100 $a20210707a20219999 -u- - 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aDimensions$ejournal of architectural knowledge 210 1$aBielefeld$ctranscript-Verlag$d2021- 215 $aOnline-Ressource 311 08$a2747-5085 608 $aZeitschrift$2gnd-content 801 0$bCH-ZuSLS ETH 906 $aJOURNAL 912 $a9910473642303321 996 $aDimensions$92122753 997 $aUNINA