LEADER 02927oam 2200589 450 001 9910137464103321 005 20230621135339.0 010 $a2-8218-1470-4 010 $a2-7226-0098-6 024 7 $a10.4000/books.cdf.191 035 $a(CKB)3170000000061028 035 $a(SSID)ssj0001541758 035 $a(PQKBManifestationID)11802994 035 $a(PQKBTitleCode)TC0001541758 035 $a(PQKBWorkID)11535624 035 $a(PQKB)11589935 035 $a(WaSeSS)IndRDA00056487 035 $a(FrMaCLE)OB-cdf-191 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/54289 035 $a(PPN)267951019 035 $a(EXLCZ)993170000000061028 100 $a20160829d2010 uy 0 101 0 $afre 135 $aur||#|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 14$aLes nanotechnologies peuvent-elles contribuer à traiter des maladies sévères /$fPatrick Couvreur 210 $cCollège de France$d2010 210 31$aFrance :$cCollège de France Fayard,$d2010 215 $a1 online resource (60 pages) $cdigital file(s) 225 1 $aLec?ons inaugurales ;$v211 300 $aBibliographic Level Mode of Issuance: Monograph 311 08$aPrint version: 9782213654928 330 $aInaugural lecture delivered on January 21, 2010, Chair of Technological Innovation Liliane Bettencourt (2009-2010). The design of nanotechnologies capable of transporting drugs in the body and releasing them in a specific manner at the level of the site of action makes it possible to increase the therapeutic activity and to reduce the toxicity of many drugs. These ?nanovectors? are capable of protecting the active molecule from degradation by the enzymes of the organism, of targeting it selectively towards the target tissue or cell, and of controlling its release. More specific than traditional pharmaceutical formulations, ?nanomedicines? make it possible to design new therapeutic strategies in the fight against severe diseases: cancers, intracellular infections, metabolic or neurodegenerative diseases, etc. The Chair of Technological Innovation at the Collège de France was created with the support of the Bettencourt-Schueller Foundation. 410 0$aLec?ons inaugurales du Colle?ge de France ;$v211. 606 $aHealth & Biological Sciences$2HILCC 606 $aBiomedical Engineering$2HILCC 610 $ainnovation technologique 610 $amédecine 610 $ananotechnologies 610 $apharmacotechnie 610 $ananomédicament 615 7$aHealth & Biological Sciences 615 7$aBiomedical Engineering 700 $aCouvreur$b Patrick$0802328 801 0$bPQKB 801 2$bUkMaJRU 906 $aBOOK 912 $a9910137464103321 996 $aNanotechnologies peuvent-elles contribuer à traiter des maladies sévères $91803635 997 $aUNINA