LEADER 02919nam 2200601 450 001 9910137238903321 005 20230621135746.0 010 $a9782889193707$b(ebook) 035 $a(CKB)3710000000506262 035 $a(SSID)ssj0001680356 035 $a(PQKBManifestationID)16496380 035 $a(PQKBTitleCode)TC0001680356 035 $a(PQKBWorkID)15028438 035 $a(PQKB)11306935 035 $a(WaSeSS)IndRDA00056375 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/53663 035 $a(EXLCZ)993710000000506262 100 $a20160829d2014 uy 0 101 0 $aeng 135 $aur||#|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aModel organisms in inflammation and cancer /$ftopic editors: Yiorgos Apidianakis and Dominique Ferrandon 210 $cFrontiers Media SA$d2014 210 31$aFrance :$cFrontiers Media SA,$d2014 215 $a1 online resource (83 pages) $cillustrations; digital, PDF file(s) 225 0 $aFrontiers Research Topics 300 $aBibliographic Level Mode of Issuance: Monograph 320 $aIncludes bibliographical references. 330 $aInflammation and cancer are two types of perturbations of organismal homeostasis that have been largely studied apart up until recently. Nowadays, it becomes increasingly clear that inflammatory responses to microbial and damaged-host stimuli facilitate tumorigenesis and cancer. Both arms of immunity, innate and adaptive, are playing a role in promoting cancer. Undoubtedly, many microbial species, well-known and opportunistic pathogens and possibly beneficial commensals, contribute to inflammation and cancer predisposition. Indeed, their influence on chronic disease is sometimes difficult to discern, especially in the context of polymicrobial communities. In this light, model organisms provide important insights into immune and growth signals that promote cancer, and suggest therapies that will selectively target harmful microbes or modulate host responses. A number of manuscripts in this series will address novel aspects and paradigms of microbiome-immunity-epithelial cell interaction that lead to carcinogenesis. 606 $aPathology$2HILCC 606 $aMedicine$2HILCC 606 $aHealth & Biological Sciences$2HILCC 610 $amicrobiota 610 $amouse 610 $ainnate immunity 610 $aDrosophila 610 $adiet 610 $aaging 610 $ahuman 610 $aHologenome 615 7$aPathology 615 7$aMedicine 615 7$aHealth & Biological Sciences 700 $aYiorgos Apidianakis$4auth$01365482 702 $aApidianakis$b Yiorgos 702 $aFerrandon$b Dominique 801 0$bPQKB 801 2$bUkMaJRU 912 $a9910137238903321 996 $aModel organisms in inflammation and cancer$93387421 997 $aUNINA