LEADER 04834nam 2200553 450 001 9910137225903321 005 20210209193440.0 010 $a3-527-69479-X 010 $a3-527-69478-1 010 $a3-527-69477-3 035 $a(CKB)3710000000515857 035 $a(MiAaPQ)EBC5015030 035 $a(MiAaPQ)EBC4529209 035 $a(Au-PeEL)EBL4529209 035 $a(CaONFJC)MIL875106 035 $a(OCoLC)944303297 035 $a(PPN)226368548 035 $a(EXLCZ)993710000000515857 100 $a20171016h20162016 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 10$aAsymmetric bronsted acid catalysis /$fMagnus Rueping, Dixit Parmar, and Erli Sugiono 205 $a1st ed. 210 1$aWeinheim, [Germany] :$cWiley-VCH Verlag GmbH & Co. KGaA,$d2016. 210 4$d©2016 215 $a1 online resource (303 pages) 311 $a3-527-33917-5 320 $aIncludes bibliographical references and index. 327 $aCover -- Title Page -- Copyright -- Contents -- Preface -- Chapter 1 Introduction -- 1.1 Book Structure and Notation -- 1.2 Catalyst Preparation -- 1.3 Metal Impurities -- References -- Chapter 2 Reactions of Imines -- 2.1 Nucleophilic Addition Reactions -- 2.1.1 C-Nucleophiles -- 2.1.2 N-Nucleophiles -- 2.1.3 O-Nucleophiles -- 2.1.4 P-Nucleophiles -- 2.2 Mannich Reactions -- 2.3 Strecker Reactions -- 2.4 Biginelli Reactions -- 2.5 Friedel-Crafts Reactions -- 2.5.1 Indole Coupling Partners with Aldimines -- 2.5.2 Indole Coupling Partners to Ketimines -- 2.5.3 Non-Indole Aromatic Partners -- 2.5.4 Pictet-Spengler Reactions -- 2.6 Transfer Hydrogenations -- 2.6.1 Imine Partners -- 2.6.2 ?-Imino Ester Partners -- 2.6.3 N-Heterocycles -- 2.6.4 Cascade Processes -- 2.6.5 Miscellaneous Reactions -- 2.7 Pericyclic Reactions -- 2.7.1 Aza-Diels-Alder/Povarov -- 2.7.2 1,3-Dipolar Cycloaddition -- 2.7.3 Electrocyclizations and Sigmatropic Rearrangements -- 2.8 Radical Reactions -- References -- Chapter 3 Reactions of Generated Imine Intermediates -- 3.1 Enamines -- 3.1.1 Nucleophilic Addition Reactions -- 3.1.2 Transfer Hydrogenation -- 3.2 Indoles Containing Leaving Groups -- 3.2.1 Nucleophilic Addition Reactions -- 3.2.2 Friedel-Crafts Reactions -- 3.3 N-Acetals and Aminals -- 3.3.1 Nucleophilic Addition Reactions -- 3.3.2 Friedel-Crafts Reactions -- 3.3.3 Transfer Hydrogenation -- 3.4 Miscellaneous Formation -- References -- Chapter 4 Reactions of Carbonyls -- 4.1 Nucleophilic Addition Reactions -- 4.1.1 C-Nucleophiles -- 4.1.2 N-, O-, and P-Nucleophiles -- 4.2 Aldol Reactions -- 4.3 Pericyclic Reactions -- 4.4 Reductions -- References -- Chapter 5 Reactions of Generated Carbonyl Intermediates -- 5.1 Enol Ethers -- 5.2 Acetals -- 5.3 Phenols Containing Leaving Groups -- References -- Chapter 6 Reactions of Alkenes -- 6.1 Nucleophilic Addition Reactions. 327 $a6.2 Friedel-Crafts Reactions -- 6.3 Pericyclic Reactions -- 6.4 Cascades -- References -- Chapter 7 Reactions of Other Substrates -- 7.1 Aziridines -- 7.2 O-Heterocycles and Ethers -- 7.3 Hydrazines and Hydrazones -- 7.4 Azo/Diazo Substrates -- 7.5 Halogens -- 7.5.1 Fluorine -- 7.5.2 Bromine -- 7.6 Oxidizing Agents -- 7.7 Miscellaneous Substrates -- References -- Experimental Protocols -- Appendix A: Catalyst Frequency -- Appendix B: Overview of Phosphoric Acids (PA) -- Appendix C: Overview of N-Phosphoramide Acids (NPA) -- Appendix D: Overview of SPINOL Phosphoric Acids (SPA) -- Appendix E: Overview of All Other Brønsted Acids (BA) -- Index -- EULA. 330 $aA much-needed overview of the synthesis of chiral Brønsted acids and their applications in various organic transformations. The internationally recognized and highly respected expert authors summarize the most significant advances in this new and dynamically progressing field, with a special emphasis on BINOL-derived phosphoric acids. They also describe other catalysts, such as C-H, TADDOL-derived Brønsted, and sulfonic acids. For easy navigation, the chapters are organized in the first instance according to reactive intermediate and then sub-divided by reaction type.An appendix with selected experimental details for benign and straight-forward procedures rounds of the book, making this the number-one information source for organic chemists in academia and industry. 606 $aCatalysis 606 $aAsymmetric synthesis 615 0$aCatalysis. 615 0$aAsymmetric synthesis. 676 $a541.395 700 $aRueping$b Magnus$0953142 702 $aParmar$b Dixit 702 $aSugiono$b Erli 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910137225903321 996 $aAsymmetric bronsted acid catalysis$92154802 997 $aUNINA