LEADER 00876nam0-2200301 --450 001 9910449556503321 005 20210430130032.0 010 $a978-88-7466-610-2 020 $aIT$b2011-8869 100 $a20210430d2011----kmuy0itay5050 ba 101 0 $aita 102 $aIT 105 $ay 001yy 200 1 $aAnime prigioniere$epercorsi educativi di pedagogia penitenziaria$fAntonio Turco 210 $aRoma$cCarocci Faber$d2011 215 $a254 p.$d23 cm 225 1 $aServizio sociale$v127 320 $aContiene bibl. (pp. 245-252) 610 0 $aEducatori penitenziari 676 $a365.66$v21$zita 700 1$aTurco,$bAntonio$f<1952- >$020858 801 0$aIT$bUNINA$gREICAT$2UNIMARC 901 $aBK 912 $a9910449556503321 952 $aCOLLEZ. 1409 (127)$b2475/2020$fFSPBC 959 $aFSPBC 996 $aAnime prigioniere$91773562 997 $aUNINA LEADER 04282nam 2200553 450 001 9910137208603321 005 20230621140345.0 010 $a9782889193967 035 $a(CKB)3710000000520128 035 $a(WaSeSS)IndRDA00057368 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/56389 035 $a(EXLCZ)993710000000520128 100 $a20160608h20152015 fy 0 101 0 $aeng 135 $aur||#|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aPlasticity of primary afferent neurons and sensory processing after spinal cord injury /$ftopic editors, Alexander G. Rabchevsky, Jeffrey C. Petruska and Charles H. Hubscher 210 $cFrontiers Media SA$d2015 210 1$a[Lausanne, Switzerland] :$cFrontiers Media SA,$d[2015] 210 4$dİ2015 215 $a1 online resource (221 pages)$cillustrations (black and white, and colour); digital file(s) 225 1 $aFrontiers Research Topics,$x1664-8714 300 $a"Frontiers in physiology" -- front cover. 311 08$aPrint version: 2889193969 320 $aIncludes bibliographical references. 330 $aTraumatic injury of the spinal cord affects the entire organism directly and indirectly. Primary injury destroys neurons and severs axons which participate in neural circuits. Secondary injuries and pathologies arise from numerous sources including systemic inflammation, consequential damage of cutaneous, muscular, and visceral tissues, and dysregulation of autonomic, endocrine and sensory-motor functions. Evidence is mounting that spinal cord injury (SCI) affects regions of the nervous system spatially remote from the injury site, as well as peripheral tissues, and alters some basic characteristics of primary afferent cell biology and physiology (cell number, size/frequency, electrophysiology, other). The degree of afferent input and processing above the lesion is generally intact, while that in the peri-lesion area is highly variable, though pathologies emerge in both regions, including a variety of pain syndromes. Primary afferent input to spinal regions below the injury and the processing of this information becomes even more important in the face of complete or partial loss of descending input because such spared sensory processing can lead to both adaptive and pathological outcomes. This issue hosts review and research articles considering mechanisms of plasticity of primary afferent neurons and sensory processing after SCI, and how such plasticity contributes to sparing and/or recovery of functions, as well as exacerbation of existing and/or emergent pathologies. A critical issue for the majority of the SCI community is chronic above-, peri-, and below-level neuropathic pain, much of which may arise, at least in part, from plasticity of afferent fibers and nociceptive circuitry. For example, autonomic dysreflexia is common hypertensive syndrome that often develops after SCI that is highly reliant on maladaptive nociceptive sensory input and processing below the lesion. Moreover, the loss of descending input leaves the reflexive components of bladder/bowel/sexual function uncoordinated and susceptible to a variety of effects through afferent fiber plasticity. Finally, proper afferent feedback is vital for the effectiveness of activity-dependent rehabilitative therapies, but aberrant nociceptive input may interfere with these approaches since they are often unchecked due to loss of descending modulation. 410 0$aFrontiers research topics. 606 $aSpinal cord 606 $aSensory neurons 610 $asensory systems 610 $asensory neurons 610 $asensory plasticity 610 $aspinal cord injury (SCI) 610 $asensory perceptions 615 0$aSpinal cord. 615 0$aSensory neurons. 700 $aJeffrey C. Petruska$4auth$01364873 702 $aRabchevsky$b Alexander G. 702 $aPetruska$b Jeffrey C. 702 $aHubscher$b Charles H. 801 0$bWaSeSS 801 1$bWaSeSS 801 2$bUkMaJRU 906 $aBOOK 912 $a9910137208603321 996 $aPlasticity of primary afferent neurons and sensory processing after spinal cord injury$93386318 997 $aUNINA