LEADER 01094nam--2200385---450- 001 990000378620203316 005 20050728130432.0 010 $a0821407228 035 $a0037862 035 $aUSA010037862 035 $a(ALEPH)000037862USA01 035 $a0037862 100 $a20010328d1986----km-y0itay0103----ba 101 $aeng 102 $aGR 105 $a||||||||001yy 200 1 $aWilla Cather's short fiction$fMarilyn Arnold 210 $aAthens$cOhio University press$d1986 215 $aXV, 198 p.$d23 cm 410 $12001 606 0 $aCather, Willa$xSaggi 676 $a81352 700 1$aARNOLD,$bMarilyn$0544058 801 0$aIT$bsalbc$gISBD 912 $a990000378620203316 951 $aVII.4.B. 179(II i B 58)$b107536 LM$c002 I B 959 $aBK 969 $aUMA 979 $aPATTY$b02$c20010328$lUSA01$h1132 979 $aPATTY$b90$c20010417$lUSA01$h1255 979 $c20020403$lUSA01$h1645 979 $aPATRY$b90$c20040406$lUSA01$h1626 979 $aCOPAT3$b90$c20050728$lUSA01$h1304 996 $aWilla Cather's short fiction$9875410 997 $aUNISA LEADER 03598nam 2200625 450 001 9910137207203321 005 20230621141341.0 010 $a9782889192809$b(ebook) 035 $a(CKB)3710000000526080 035 $a(SSID)ssj0001680342 035 $a(PQKBManifestationID)16496334 035 $a(PQKBTitleCode)TC0001680342 035 $a(PQKBWorkID)15028408 035 $a(PQKB)10513550 035 $a(WaSeSS)IndRDA00056299 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/53402 035 $a(EXLCZ)993710000000526080 100 $a20160829d2014 uy | 101 0 $aeng 135 $aur||#|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aMicrobial modulation of host apoptosis and pyroptosis /$ftopic editors: Yongqun He and Amal O. Amer 210 $cFrontiers Media SA$d2014 210 31$aFrance :$cFrontiers Media SA,$d2014 215 $a1 online resource (109 pages) $cillustrations; digital, PDF file(s) 225 0 $aFrontiers Research Topics 300 $aBibliographic Level Mode of Issuance: Monograph 320 $aIncludes bibliographical references. 330 $aInfectious disease is the result of an interactive relationship between a microbial pathogen and its host. In this interaction both the host and the pathogen attempt to manipulate each other using a complex network to maximize their respective survival probabilities. Programmed host cell death is a direct outcome of host-pathogen interaction and may benefit host or pathogen depending on microbial pathogenesis. Apoptosis and pyroptosis are two common programmed cell death types induced by various microbial infections. Apoptosis is non-inflammatory programmed cell death and can be triggered through intrinsic or extrinsic pathways and with or without the contribution of mitochondria. Pyroptosis is an inflammatory cell death and is typically triggered by caspase-1 after its activation by various inflammasomes. Microbial pathogens are able to modulate host apoptosis and pyroptosis through different triggers and pathways. The promotion and inhibition of host apoptosis and pyroptosis vary and depend on the microbe types, virulence, and phenotypes. For example, virulent pathogens and attenuated vaccine strains may use different pathways to modulate host cell death. Specific microbial genes may be responsible for the modulation of host cell death. Different host cells, including macrophages, dendritic cells, and T cells, can undergo apoptosis and pyroptosis after microbial infections. The pathways of host apoptosis and pyroptosis induced by different microbes may also differ. Different methods can be used to study the interaction between microbes and host cell death system. 606 $aCytology$2HILCC 606 $aBiology$2HILCC 606 $aHealth & Biological Sciences$2HILCC 610 $amicrobial infection 610 $apyroptosis 610 $aMycobacterium tuberculosis 610 $abacterial exploitation of apoptosis 610 $aBrucella 610 $aInfectious Disease 610 $aInflammasome 610 $aLegionella 610 $aprogrammed cell death 610 $aApoptosis 615 7$aCytology 615 7$aBiology 615 7$aHealth & Biological Sciences 700 $aAmal O. Amer$4auth$01363583 702 $aHe$b Yongqun 702 $aAmer$b Amal O 801 0$bPQKB 801 2$bUkMaJRU 912 $a9910137207203321 996 $aMicrobial modulation of host apoptosis and pyroptosis$93384340 997 $aUNINA