LEADER 02834nam 2200445 450 001 9910137200003321 005 20230621140326.0 010 $a9782889192939$b(ebook) 035 $a(CKB)3710000000526108 035 $a(WaSeSS)IndRDA00058211 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/59321 035 $a(EXLCZ)993710000000526108 100 $a20160623d2014 uy 0 101 0 $aeng 135 $aur||#|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aShiga toxin-producing Escherichia coli in human, cattle and foods $estrategies for detection and control /$ftopic editors, Nora Li?a Padola and Anali?a I. Etcheverri?a 210 $cFrontiers Media SA$d2014 210 1$a[Lausanne, Switzerland] :$cFrontiers Media SA,$d2014. 215 $a1 online resource (107 pages) $cdigital, PDF file(s) 225 0 $aFrontiers Research Topics 320 $aIncludes bibliographical references. 330 $aShiga toxin-producing Escherichia coli (STEC) is an important foodborne pathogen associated with both outbreaks and sporadic cases of human disease, ranging from uncomplicated diarrhoea to haemorrhagic colitis (HC) and haemolytic uraemic syndrome (HUS). STEC affects children, elderly and immuno-compromised patients. STEC is capable of producing Shiga toxin type 1 (Stx1), type 2 (Stx2) or both, encoded by stx1 and stx2 genes, respectively. These strains are likely to produce putative accessory virulence factors such as intimin (encoded by eae), an enterohaemolysin (EhxA) and an autoagglutinating protein commonly associated with eae-negative strains (Saa), both encoded by an enterohaemorrhagic plasmid. Several studies have confirmed that cattle are the principal reservoir of STEC (O157 and non-O157:H7 serotypes) and many of these serotypes have been involved in HUS and HC outbreaks in other countries. Transmission of STEC to humans occurs through the consumption of undercooked meat, vegetables and water contaminated by faeces of carriers and by person-to-person contact. Diagnostic methods have evolved to avoid selective diagnostics, currently using molecular techniques for typing and subtyping of strains. Control is still a challenge, although there are animal vaccines directed against the serotype O157:H7. 606 $aEscherichia coli 610 $aenvironment 610 $aCattle 610 $aSTEC 610 $aVirulence Factors 610 $aFood 615 0$aEscherichia coli. 700 $aNora Lia Padola$4auth$01367188 702 $aPadola$b Nora Li?a 702 $aEtcheverri?a$b Anali?a I. 801 0$bWaSeSS 801 2$bUkMaJRU 912 $a9910137200003321 996 $aShiga toxin-producing Escherichia coli in human, cattle and foods$93389918 997 $aUNINA