LEADER 02454nam  2200421z- 450 
001 9910137100003321
005 20231214133041.0
035   $a(CKB)3710000000824697
035   $a(oapen)https://directory.doabooks.org/handle/20.500.12854/54693
035   $a(EXLCZ)993710000000824697
100   $a20202102d2015      |y             0
101 0 $aeng
135   $aurmn|---annan
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aNLR-protein functions in immunity
210   $cFrontiers Media SA$d2015
215   $a1 electronic resource (220 p.)
225 1 $aFrontiers Research Topics
311   $a2-88919-621-6 
330   $aThe Nod-like receptor (NLR) family of proteins are evolutionary conserved molecules that in plants and mammals have been implicated in innate immune sensing of microbes and infection-associated physiological changes, contributing to immune protection of the challenged host organism through the instruction of inflammatory responses, antimicrobial defense and adaptive immunity. Recent data however suggests that the biological roles of NLR go beyond the function of classical pattern recognition molecules (PRM) as they have been implicated in essential cellular processes including autophagy, apoptosis, modification of signal transduction and gene transcription as well as reproductive biology. In this research topic, we aim to provide a comprehensive state-of the art overview of the emerging functions of NLR in plant and mammalian immunity, cell biology and reproductive biology. Potential topics may include, but are not limited to the following areas: ? Functions of NLRs as PRMs in infection ? Cross-talk of NLRs with other PRMs ? Signal transduction pathways of NLRs ? New functions of NLRs other than pattern recognition ? Structural aspects of NLR activation ? Mechanisms of NLRs in cell biological processes ? Aspects of NLRs in reproductive biology ? Functions of NLRs in plant immune responses
610   $aAdaptive Immunity
610   $aPAMP
610   $apathogens
610   $aMAMP
610   $ainnate immunity
610   $aBacteria
610   $aSensing
610   $avirus
610   $aLRR
610   $aDAMP
700   $aJorg H. Fritz$4auth$01296298
702   $aThomas A. Kufer$4auth
906   $aBOOK
912   $a9910137100003321
996   $aNLR-protein functions in immunity$93023972
997   $aUNINA