LEADER 03083nam  2200589   450 
001 9910137099603321
005 20230807212030.0
035   $a(CKB)3710000000824699
035   $a(oapen)https://directory.doabooks.org/handle/20.500.12854/40880
035   $a(EXLCZ)993710000000824699
100   $a20160822d2015uuuu  fu|            0
101 0 $aeng
135   $aurc|#---|||||
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 00$aAnimal allergens$b[electronic resource] $ecommon protein characteristics featuring their allergenicity /$fedited by Christiane Hilger and Annette Kuehn
210   $cFrontiers Media SA$d2015
210  1$a[Place of publication not identified] :$cFrontiers Media SA,$d2015.
215   $a1 online resource (88 pages) $cillustrations; digital, PDF file(s)
225 0 $aFrontiers research topics
225 1 $aFrontiers in immunology
300   $aPublished in: Frontiers in immunology.
311   $a2-88919-620-8 
320   $aIncludes bibliographical references.
330 3 $aAmong the many molecules present in our environment, some have the property to induce allergic sensitization and IgE-mediated reactions. The analysis of known major animal allergens has shown that most belong to single protein families: lipocalins and serum albumins for inhalant allergens, EF-hand proteins, tropomyosins and caseins for the digestive allergens. The finding that allergens are often clustered in large families may be related to the fact that common structural, biochemical or functional features contribute to their allergenicity, in addition to external adjuvant factors. Currently, there is no curative treatment for animal allergy available. In order to lower allergic reactions to respiratory allergens in daily life and to food allergens upon accidental exposure, it is important to desensitize concerned patients. Tolerance induction by allergen-specific immunotherapy is in the current focus of an ambitious research. This Research Topic aims to provide a comprehensive view of the basic and recent insights on the allergenicity of animal allergens in view of their structural and functional aspects as well as allergen-specific immunotherapy.
410  0$aFrontiers in immunology.
606   $aImmunologic diseases
606   $aAllergens
606   $aAllergy and immunology
606   $aAllergens$ximmunology
610   $aallergen exposure
610   $aisoallergens
610   $aimmune response
610   $aImmunotherapy
610   $abiological function
610   $aallergy
610   $across-reactivity
610   $aAllergenicity
610   $aAnimal allergen
615  0$aImmunologic diseases.
615  0$aAllergens.
615  0$aAllergy and immunology.
615  2$aAllergens$ximmunology.
700   $aChristiane Hilger$4auth$01376539
702   $aHilger$b Christiane
702   $aKuehn$b Annette
801  2$bUkMaJRU
906   $aBOOK
912   $a9910137099603321
996   $aAnimal allergens$93412434
997   $aUNINA