LEADER 02295nam 2200457z- 450 001 9910137093103321 005 20210211 035 $a(CKB)3710000000824727 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/52683 035 $a(oapen)doab52683 035 $a(EXLCZ)993710000000824727 100 $a20202102d2015 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aManipulation of the cellular microbicidal response and endocytic dynamic by pathogens membrane factors 210 $cFrontiers Media SA$d2015 215 $a1 online resource (81 p.) 225 1 $aFrontiers Research Topics 311 08$a2-88919-609-7 330 $aIntracellular pathogens, such as bacteria and parasites, have evolved specialized mechanisms to survive and replicate in their host, leading to disorders and diseases. The principle of these mechanisms is to reprogram the microbicidal cell function in order to disable the host cells defence that aims to control and eliminate foreign invaders. Devoid of their defence, cells become permissive to pathogens invasion. The aim of this Research Topic is to highlight and cover recent understanding of mechanisms and molecules used by pathogens to interfere with the microbicidal function of cells. This Research Topic will focus on the reprogramming of the cellular dynamics, the immune response, the phagolysosome biogenesis and the signal transduction pathways bypathogens. Special attention will be made on non-proteic virulence factors, however this Research Topic is not restricted to non-proteic virulence factors. 610 $aBody Lices 610 $aBrucella 610 $aCoxiella 610 $agranulomas 610 $ahost-pathogens interaction 610 $aLeshmania 610 $amycobacteria 610 $aPlanarians 610 $arab 610 $aRNAi 610 $aUbiquitination 700 $aBenjamin Coiffard$4auth$01287809 702 $aEric Ghigo$4auth 702 $aPhilippe Soubeyran$4auth 906 $aBOOK 912 $a9910137093103321 996 $aManipulation of the cellular microbicidal response and endocytic dynamic by pathogens membrane factors$93020432 997 $aUNINA