LEADER 05009nam 2200697 450 001 9910136822903321 005 20230808192253.0 010 $a1-118-72833-5 010 $a1-118-72830-0 035 $a(CKB)3710000000621161 035 $a(EBL)4454974 035 $a(SSID)ssj0001645587 035 $a(PQKBManifestationID)16414309 035 $a(PQKBTitleCode)TC0001645587 035 $a(PQKBWorkID)14916065 035 $a(PQKB)11437777 035 $a(PQKBManifestationID)16342719 035 $a(PQKBWorkID)14916064 035 $a(PQKB)24882156 035 $a(MiAaPQ)EBC4454974 035 $a(DLC) 2016009650 035 $a(Au-PeEL)EBL4454974 035 $a(CaPaEBR)ebr11176433 035 $a(CaONFJC)MIL909433 035 $a(OCoLC)942610793 035 $a(EXLCZ)993710000000621161 100 $a20151204d2016 uy| 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt 182 $cc 183 $acr 200 00$aClostridial diseases of animals /$f[edited by] Francisco Alejandro Uzal, John Francis Prescott, J. Glenn Songer, Michel Robert Popoff 210 1$aAmes, Iowa :$cJohn Wiley & Sons, Incorporated,$d2016. 215 $a1 online resource (427 p.) 300 $aDescription based upon print version of record. 311 $a1-118-72840-8 311 $a1-118-72829-7 320 $aIncludes bibliographical references and index. 327 $aTitle Page; Copyright Page; Contents; List of Contributors; Preface; SECTION 1 The Pathogenic Clostridia; Chapter 1 Taxonomic Relationships among the Clostridia; Bibliography; Chapter 2 General Physiological and Virulence Properties of the Pathogenic Clostridia; Introduction; Anaerobic metabolism; Major clostridial diseases; The onset of clostridial infections; The key role of protein toxins in clostridial disease; The key role of spores in the epidemiology of clostridial disease; Conclusions; Bibliography; Chapter 3 Brief Description of Animal Pathogenic Clostridia; Bibliography 327 $aSECTION 2 Toxins Produced by the Pathogenic Clostridia Chapter 4 Toxins of Histotoxic Clostridia: Clostridium chauvoei, Clostridium septicum, Clostridium novyi, and Clostridium sordellii; Introduction; A - Intracellularly active toxins from histotoxic clostridia; B - Membrane-damaging toxins from histotoxic clostridia; Phospholipases; Bibliography; Chapter 5 Toxins of Clostridium perfringens; Introduction; A - Major toxins; B - Other toxins; Bibliography; Chapter 6 Toxins of Clostridium difficile; Introduction; Toxins A and B; C. difficile ADP-ribosylating toxin (CDT) 327 $aHypervirulence of C. difficile and its potential mechanisms Immunotherapy of C. difficile infections; Conclusion; Bibliography; Chapter 7 Clostridium botulinum and Clostridium tetani neurotoxins; Introduction; Clostridia producing botulinum neurotoxins; Clostridium tetani; Susceptibility of animal species to clostridial neurotoxins; Structure of clostridial neurotoxins; Mode of action of clostridial neurotoxins; Concluding remarks; Bibliography; SECTION 3 Clostridial Infections of the Gastrointestinal System; Chapter 8 Diseases produced by Clostridium perfringens type A in mammalian species 327 $aIntroduction Yellow lamb disease; Other enteric diseases produced by Clostridium perfringens type A in mammals; Clostridium perfringens beta 2 toxin-associated gastrointestinal disease; Bibliography; Chapter 9 NetF-associated necrotizing enteritis of foals and canine hemorrhagic gastroenteritis; Introduction; Etiology; Epidemiology and clinical findings; Gross changes; Microscopic changes; Diagnosis; Bibliography; Chapter 10 Necrotic enteritis of poultry; Introduction; Epidemiology; Etiology and pathogenesis; Host response; Predisposing factors; Clinical signs; Gross changes 327 $aMicroscopic changes Prophylaxis; Diagnosis; Bibliography; Chapter 11 Infections by Clostridium perfringens type B; Introduction; Etiology; Clinical signs; Gross changes; Microscopic changes; Diagnosis; Prevention and treatment; Bibliography; Chapter 12 Diseases produced by Clostridium perfringens type C; Diseases of mammalian species; Necrotic enteritis of poultry; Bibliography; Chapter 13 Diseases Produced by Clostridium perfringens type D; Introduction; Etiology; Epidemiology and pathogenesis; Clinical signs; Gross changes; Microscopic changes; Diagnosis; Prophylaxis and treatment 327 $aBibliography 606 $aClostridium diseases in animals 606 $aClostridium 615 0$aClostridium diseases in animals. 615 0$aClostridium. 676 $a636.089/6931 702 $aUzal$b Francisco Alejandro$f1958- 702 $aPrescott$b John F$g(John Francis),$f1949- 702 $aSonger$b J. Glenn$g(Joseph Glenn),$f1950- 702 $aPopoff$b Michel R. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910136822903321 996 $aClostridial diseases of animals$92189330 997 $aUNINA