LEADER 02080nam 2200373z- 450 001 9910136806403321 005 20231214133452.0 035 $a(CKB)3710000000631083 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/53848 035 $a(EXLCZ)993710000000631083 100 $a20202102d2016 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aMolecular mechanisms for reprogramming hippocampal development and function by early-life stress 210 $cFrontiers Media SA$d2016 215 $a1 electronic resource (100 p.) 225 1 $aFrontiers Research Topics 311 $a2-88919-806-5 330 $aThe early postnatal period is a crucial stage for hippocampal development. During this critical period, the neonatal hippocampus is highly sensitive to the detrimental consequences of adverse environmental factors. Extensive clinical and preclinical evidence has shown that traumatic events early in life have profound and persistent effects on hippocampal function and behavior. This research topic focuses on the acute and lasting effects of early-life stress on various developmental processes in the hippocampus, and aims to uncover the molecules that are responsible for early-life stress-programmed effects and underlie resilience or vulnerability to stress-related neuropsychiatric disorders later in life. We hope the articles in this research topic will provide novel insights and stimulate future studies on the mechanisms of early-life stress and brain development. 610 $adevelopment 610 $amolecular mechanism 610 $aearly-life stress 610 $aplasticity 610 $aHippocampus 610 $apsychiatric disorders 700 $aMathias V. Schmidt$4auth$01286169 702 $aXiao-Dong Wang$4auth 906 $aBOOK 912 $a9910136806403321 996 $aMolecular mechanisms for reprogramming hippocampal development and function by early-life stress$93019735 997 $aUNINA