LEADER 01964nam  2200385z- 450 
001 9910136806303321
005 20231214133444.0
035   $a(CKB)3710000000631084
035   $a(oapen)https://directory.doabooks.org/handle/20.500.12854/52929
035   $a(EXLCZ)993710000000631084
100   $a20202102d2016      |y             0
101 0 $aeng
135   $aurmn|---annan
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aMechanical Loading and Bone
210   $cFrontiers Media SA$d2016
215   $a1 electronic resource (99 p.)
225 1 $aFrontiers Research Topics
311   $a2-88919-751-4 
330   $aThis research topic is focused on recent advances in our understanding of effects of mechanical loading on the skeleton, and research methods used in addressing these. Though it is well established that mechanical loading provides an essential stimulus for skeletal growth and maintenance, there have been major advances recently in terms of our understanding of the molecular pathways involved, which are thought to provide novel drug targets for treating osteoporosis. The articles included in this topic encompass the full spectrum of laboratory and clinical research, and range from review articles, editorials, hypothesis papers and original research articles. Together, they demonstrate how mechanical loading underpins many aspects of bone biology, including the pathogenesis and treatment of osteoporosis and other clinical disorders associated with skeletal fragility.
610   $amechanical loading
610   $abone architecture
610   $aaccelerometers
610   $aosteoblast
610   $aosteoporosis
610   $aosteoclast
610   $afractures
610   $adistraction osteogenesis
700   $aJonathan H. Tobias$4auth$01331573
906   $aBOOK
912   $a9910136806303321
996   $aMechanical Loading and Bone$93040445
997   $aUNINA