LEADER 00873nam 22003133 450 001 9910131662703321 005 20231115133734.0 035 $a(CKB)3460000000088176 035 $a(ItFiC)it 002448593 035 $a(EXLCZ)993460000000088176 100 $a20110322d2009 uy 0 101 0 $aita 200 02$aL'ontologia imperfetta /$fGiovanni Cera 210 $aBari $cEdizioni di Pagina$d2009 215 $a100 p. ;$d19 cm 225 0$aDue punti ;$v10 300 $aG. Cera teaches at the Universities of Bari and Foggia. 311 $a9788874700950 320 $aIncludes bibliographical references. 676 $a128 676 $a111 676 $a121 700 $aCera$b Giovanni$f1943-$01022605 801 0$bItFiC 801 1$bItFiC 906 $aBOOK 912 $a9910131662703321 996 $aL'ontologia imperfetta$92438776 997 $aUNINA LEADER 02063oam 2200613I 450 001 9910779969503321 005 20230607212955.0 010 $a1-134-53819-7 010 $a1-138-16322-8 010 $a1-134-53820-0 010 $a1-280-10933-5 010 $a0-203-45344-1 024 7 $a10.4324/9780203453445 035 $a(CKB)111056485343696 035 $a(EBL)167122 035 $a(OCoLC)264443649 035 $a(SSID)ssj0000121226 035 $a(PQKBManifestationID)11141074 035 $a(PQKBTitleCode)TC0000121226 035 $a(PQKBWorkID)10092601 035 $a(PQKB)11002025 035 $a(MiAaPQ)EBC167122 035 $a(Au-PeEL)EBL167122 035 $a(CaPaEBR)ebr10096535 035 $a(CaONFJC)MIL10933 035 $a(OCoLC)51977251 035 $a(EXLCZ)99111056485343696 100 $a20180706d2002 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 14$aThe child's mind /$fJohn White 210 1$aNew York :$cRoutledgeFalmer,$d2002. 215 $a1 online resource (219 p.) 300 $aDescription based upon print version of record. 311 $a0-415-24783-7 311 $a0-203-26234-4 320 $aIncludes bibliographical references and index. 327 $aBook Cover; Title; Contents; Acknowledgements; Introduction; What is the child's mind?; Concepts and concept learning; Beliefs: maps by which we steer; Do minds develop?; Who needs intelligence?; What is thinking?; Imagination and creativity; Motivating children; Educating the emotions; The whole child; Appendix More about minds; Works referred to in the text; Index 606 $aCognition in children 606 $aChild psychology 615 0$aCognition in children. 615 0$aChild psychology. 676 $a155.4/13 676 $a370.15 700 $aWhite$b John$f1934 Nov. 7-,$0887430 801 0$bFlBoTFG 801 1$bFlBoTFG 906 $aBOOK 912 $a9910779969503321 996 $aThe child's mind$93819590 997 $aUNINA LEADER 03462nam 2200373z- 450 001 9910136804703321 005 20210211 035 $a(CKB)3710000000631093 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/54346 035 $a(oapen)doab54346 035 $a(EXLCZ)993710000000631093 100 $a20202102d2015 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aThe Natriuretic Hormones 210 $cFrontiers Media SA$d2015 215 $a1 online resource (76 p.) 225 1 $aFrontiers Research Topics 311 08$a2-88919-709-3 330 $aThe title follows from the original demonstration by Dr. Hugh de Wardener in 1961 that a humoral agent is produced after extracellular volume expansion which results in a vigorous diuresis and natriuresis. Thus the name of "natriuretic hormone" was coined. In the years that followed several investigators pursued the search for the hormone. What resulted, however, was the discovery of several hormones with different characteristics, all of which were natriuretic. Initially it was found that the hormone was similar in action to ouabain or digoxin, hence the appelation of ouabain-like or digoxin-like. The hormone was found to be an inhibitor of Na-K-ATPase, which would fit with it being a cardiotonic steroid. On the other hand, neither ouabain or digoxin migrated on Sephadex gel filtration in the same locus as the hormone. Other investigators claim to have identified the hormone-initially as a vanadium-diascorbate, later as bufadienolides such as marinobufagenin, yet later as a macrocylic derivative of inorganic carbon suboxide with a molecular weight of 408 Da. Some support for the latter finding was derived from an earlier report that a semi-purified Sephadex-derived compound was found to have a molecular weight of about 12,000 Da but the active compound, when split from its carrier protein, had a molecular weight of exactly 408 Da. This compound had not been further identified. As further development was the demonstration by Bricker and colleagues that a natriuretic substance could be purified from uremic urine. This turned out to be a xathurenic acid derivative. Meanwhile the focus began to turn to natriuretic peptides derived from heart (ANF and BNP). These peptides have a shorter duration of action than the cardiotonic steroid-like hormone and ANF has proved to be most useful as a measure of heart failure. It should also be stressed that marinobufagenin, like ANF, is elevated in congestive heart failure, whereas the steroid-like hormone is depressed or absent in this state. This review will attempt to describe and contrast the properties of each of the proposed natriuretic hormones, including their locus on Sephadex separation, potency, duration of action, chemical structure (if known), behavior in hypertension, renal failure, heart failure, and brain disease. As most recent work has focussed on marinobufagenin, this hormone will be brought up to date by investigators in the field. 610 $ahormone 610 $aHypertension 610 $aHypothalamus 610 $aNatriuresis 610 $aVolume expansion 700 $aVardaman M. Buckalew$4auth$01332386 702 $aHarvey Craig Gonick$4auth 906 $aBOOK 912 $a9910136804703321 996 $aThe Natriuretic Hormones$93040925 997 $aUNINA