LEADER 01258nam a2200337 i 4500 001 991000704159707536 005 20020507172509.0 008 951019s1983 us ||| | eng 020 $a0387908102 035 $ab10745567-39ule_inst 035 $aLE01300978$9ExL 040 $aDip.to Matematica$beng 082 0 $a519.544 084 $aAMS 62G99 100 1 $aBasawa, Ishwar V.$014353 245 10$aAsymptotic optimal inference for non-ergodic models /$cIshwar V. Basawa, David John Scott 260 $aNew York :$bSpringer-Verlag,$cc1983 300 $aix, 170 p. ;$c24 cm. 490 0 $aLecture notes in statistics ;$v17 500 $aBibliography: p. [161]-170 650 4$aAsymptotic efficiencies 650 4$aErgodic theory 650 4$aEstimation theory 650 4$aNonparametric inference 700 1 $aScott, David John$eauthor$4http://id.loc.gov/vocabulary/relators/aut$0736354 907 $a.b10745567$b23-02-17$c28-06-02 912 $a991000704159707536 945 $aLE013 62G BAS11 (1983)$g1$i2013000037899$lle013$o-$pE0.00$q-$rl$s- $t0$u1$v0$w1$x0$y.i10837632$z28-06-02 996 $aAsymptotic optimal inference for non-ergodic models$91455386 997 $aUNISALENTO 998 $ale013$b01-01-95$cm$da $e-$feng$gus $h0$i1 LEADER 02868nam 2200457z- 450 001 9910136803103321 005 20210212 035 $a(CKB)3710000000631102 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/58581 035 $a(oapen)doab58581 035 $a(EXLCZ)993710000000631102 100 $a20202102d2015 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aThe Role of Glia in Plasticity and Behavior 210 $cFrontiers Media SA$d2015 215 $a1 online resource (104 p.) 225 1 $aFrontiers Research Topics 311 08$a2-88919-690-9 330 $aGlial cells are no longer considered passive bystanders in neuronal brain circuits. Not only are they required for housekeeping and brain metabolism, they are active participants in regulating the physiological function and plasticity of brain circuits and the online control of behavior both in invertebrate and vertebrate model systems. In invertebrates, glial cells are essential for normal function of sensory organs (C. elegans) and necessary for the circadian regulation of locomotor activity (D. melanogaster). In the mamallian brain, astrocytes are implicated in the regulation of cortical brain rhythms and sleep homeostasis. Disruption of AMPA receptor function in a subset of glial cell types in mice shows behavioral deficits. Furthermore, genetic disruption of glial cell function can directly control behavioral output. Regulation of ionic gradients by glia can underlie bistability of neurons and can modulate the fidelity of synaptic transmission. Grafting of human glial progenitor cells in mouse forebrain results in human glial chimeric mice with enhanced plasticity and improved behavioral performance, suggesting that astrocytes have evolved to cope with information processing in more complex brains. Taken together, current evidence is strongly suggestive that glial cells are essential contributors to information processing in the brain. This Research Topic compiles recent research that shows how the molecular mechanisms underlying glial cell function can be dissected, reviews their impact on plasticity and behavior across species and presents novel approaches to further probe their function. 606 $aNeurosciences$2bicssc 610 $aAstrocytes 610 $aBehavior 610 $aC. elegans 610 $aCerebellum 610 $aCortex 610 $aDREADD 610 $aglia 610 $aGq 610 $aHippocampus 610 $aplasticity 615 7$aNeurosciences 700 $aTycho Hoogland$4auth$01332333 702 $aParpura$b Vladimir$f1964-$4auth 906 $aBOOK 912 $a9910136803103321 996 $aThe Role of Glia in Plasticity and Behavior$93040850 997 $aUNINA