LEADER 02003nam 2200409z- 450 001 9910136800303321 005 20210212 035 $a(CKB)3710000000631119 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/60449 035 $a(oapen)doab60449 035 $a(EXLCZ)993710000000631119 100 $a20202102d2015 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aT Cell Regulation by the Environment 210 $cFrontiers Media SA$d2015 215 $a1 online resource (115 p.) 225 1 $aFrontiers Research Topics 311 08$a2-88919-733-6 330 $aNai?ve T cells get activated upon encounter with their cognate antigen and differentiate into a specific subset of effector cells. These T cells are themselves plastic and are able to re-differentiate into another subset, changing both phenotype and function. Differentiation into a specific subset depends on the nature of the antigen and of the environmental milieu. Notably, certain nutrients, such as vitamins A and D, sodium chloride, have been shown to modulate T cell responses and influence T cell differentiation. Parasite infection can also skew Th differentiation. Similarly, the gut microbiota regulates the development of immune responses. Lastly, the key role of metabolism on T cells has also been demonstrated. This series of articles highlights some of the multiple links existing between environmental factors and T cell responses. 606 $aMedicine and Nursing$2bicssc 610 $ahelminth 610 $aMetabolism 610 $amicrobiome 610 $aregulatory T cells 610 $aT cells 610 $aVitamin D 615 7$aMedicine and Nursing 700 $aAnne L. Astier$4auth$01328825 702 $aDavid A. Hafler$4auth 906 $aBOOK 912 $a9910136800303321 996 $aT Cell Regulation by the Environment$93039001 997 $aUNINA LEADER 00907nam0 22002411i 450 001 UON00030368 005 20231205102058.604 100 $a20020107f |0itac50 ba 101 $aeng 102 $aUN 105 $a|||| ||||| 200 1 $aGeography of Turkey$fResat Izbirak$gtransl. by Faruk Senturk 210 $a[s.l.$cs.e.]$d19- 215 $a286 p., c. di tav.rip.$cill.$d29 cm 606 $aTurchia$xGeografia$3UONC002036$2FI 686 $aTUR VIII A$cTURCHIA - GEOGRAFIA/VIAGGI - GEOGRAFIA$2A 700 1$aIZBIRAK$bResat$3UONV020296$0500952 801 $aIT$bSOL$c20251010$gRICA 899 $aSIBA - SISTEMA BIBLIOTECARIO DI ATENEO$2UONSI 912 $aUON00030368 950 $aSIBA - SISTEMA BIBLIOTECARIO DI ATENEO$dSI TUR VIII A 006 $eSI SA 52573 5 006 996 $aGeography of Turkey$91191010 997 $aUNIOR