LEADER 01903nam  2200373z- 450 
001 9910136800303321
005 20231214132847.0
035   $a(CKB)3710000000631119
035   $a(oapen)https://directory.doabooks.org/handle/20.500.12854/60449
035   $a(EXLCZ)993710000000631119
100   $a20202102d2015      |y             0
101 0 $aeng
135   $aurmn|---annan
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aT Cell Regulation by the Environment
210   $cFrontiers Media SA$d2015
215   $a1 electronic resource (115 p.)
225 1 $aFrontiers Research Topics
311   $a2-88919-733-6 
330   $aNaïve T cells get activated upon encounter with their cognate antigen and differentiate into a specific subset of effector cells. These T cells are themselves plastic and are able to re-differentiate into another subset, changing both phenotype and function. Differentiation into a specific subset depends on the nature of the antigen and of the environmental milieu. Notably, certain nutrients, such as vitamins A and D, sodium chloride, have been shown to modulate T cell responses and influence T cell differentiation. Parasite infection can also skew Th differentiation. Similarly, the gut microbiota regulates the development of immune responses. Lastly, the key role of metabolism on T cells has also been demonstrated. This series of articles highlights some of the multiple links existing between environmental factors and T cell responses.
610   $aregulatory T cells
610   $aVitamin D
610   $ahelminth
610   $aT cells
610   $aMetabolism
610   $amicrobiome
700   $aAnne L. Astier$4auth$01328825
702   $aDavid A. Hafler$4auth
906   $aBOOK
912   $a9910136800303321
996   $aT Cell Regulation by the Environment$93039001
997   $aUNINA