LEADER 04208nam 22007335 450 001 9910136610903321 005 20200704024932.0 010 $a9783319457611 024 7 $a10.1007/978-3-319-45761-1 035 $a(CKB)3710000000902973 035 $a(EBL)4718099 035 $a(DE-He213)978-3-319-45761-1 035 $a(MiAaPQ)EBC4718099 035 $a(PPN)196326257 035 $a(EXLCZ)993710000000902973 100 $a20161014d2017 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aEnvironmental Radiation Effects on Mammals $eA Dynamical Modeling Approach /$fby Olga A. Smirnova 205 $a2nd ed. 2017. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2017. 215 $a1 online resource (374 p.) 300 $aIncludes index. 311 $a3-319-45759-4 311 $a3-319-45761-6 327 $aEffects of Acute and Chronic Irradiation on the Blood-Forming System -- Effects of Non-Uniform Acute Irradiation on the Blood-Forming System. - The Small Intestine as a Target for Radiation -- Radiation and Humoral Immunity -- Modeling of Autoimmune Processes -- Individual-Based Approach to Risk Assessment of Radiation-Induced Mortality -- Effects of Acute and Chronic Irradiation on Human Hematopoiesis. - Radiogenic Leukemia Risk Assessment. - Radiation and Skin. - Conclusions -- Index. 330 $aDr. Smirnova's updated text is devoted to the theoretical studies of radiation effects on mammals. It summarizes 35 years of results the author obtained from analyzing dose rate equivalents for the Galactic Cosmic Rays (GCR) and for Solar Particles Events (SPE). This edition also includes two new chapters on skin epidermal epithelium and risk assessment for myeloid leukemia, as well as extended revisions addressing the radiation effects on the blood-forming system. Mathematical models are used to explain the effects of both acute and chronic irradiation on the dynamics of vital body systems, like the hematopoietic system, the development of autoimmune diseases, and the mortality dynamics in homogeneous and nonhomogeneous mammalian populations. The proposed methodology of these studies, the models themselves, and the obtained results are of a great theoretical significance and can find wide practical use. . 606 $aBiophysics 606 $aBiological physics 606 $aOccupational medicine 606 $aAerospace engineering 606 $aAstronautics 606 $aRadiology 606 $aAnimal physiology 606 $aBiomathematics 606 $aBiological and Medical Physics, Biophysics$3https://scigraph.springernature.com/ontologies/product-market-codes/P27008 606 $aOccupational Medicine/Industrial Medicine$3https://scigraph.springernature.com/ontologies/product-market-codes/H42001 606 $aAerospace Technology and Astronautics$3https://scigraph.springernature.com/ontologies/product-market-codes/T17050 606 $aImaging / Radiology$3https://scigraph.springernature.com/ontologies/product-market-codes/H29005 606 $aAnimal Physiology$3https://scigraph.springernature.com/ontologies/product-market-codes/L33030 606 $aMathematical and Computational Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/M31000 615 0$aBiophysics. 615 0$aBiological physics. 615 0$aOccupational medicine. 615 0$aAerospace engineering. 615 0$aAstronautics. 615 0$aRadiology. 615 0$aAnimal physiology. 615 0$aBiomathematics. 615 14$aBiological and Medical Physics, Biophysics. 615 24$aOccupational Medicine/Industrial Medicine. 615 24$aAerospace Technology and Astronautics. 615 24$aImaging / Radiology. 615 24$aAnimal Physiology. 615 24$aMathematical and Computational Biology. 676 $a530 700 $aSmirnova$b Olga A$4aut$4http://id.loc.gov/vocabulary/relators/aut$0821811 906 $aBOOK 912 $a9910136610903321 996 $aEnvironmental Radiation Effects on Mammals$92012835 997 $aUNINA