LEADER 03243nam 2200529 450 001 9910136584103321 035 $a(CKB)3710000000903214 035 $a(EBC)4717915 035 $a(OCoLC)962195173 035 $a(CaBNvSL)swl00406910 035 $a(MiAaPQ)EBC4717915 035 $a(EXLCZ)993710000000903214 100 $a20161105d2017 fy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 10$aNerve disease ALS and gradual loss of muscle function $eamytrophic lateral sclerosis /$fMary E. Miller 205 $aFirst edition. 210 1$aNew York, [New York] (222 East 46th Street, New York, NY 10017) :$cMomentum Press,$d2017. 215 $a1 online resource (xiii, 39 pages) $cillustrations 225 1 $aHuman diseases and conditions collection 320 $aIncludes bibliographical references (pages 27-29) and index. 327 $a1. Symptoms and diagnosis -- 2. Causes and contributing factors -- 3. Treatment and therapy -- 4. Future prospects -- Conclusion -- Bibliography -- Glossary -- About the author -- Index. 330 3 $aAmyotrophic lateral sclerosis, ALS, is a common form of motor neuron disease that involves a loss of function in upper and lower motor neurons. ALS causes a progressive loss of muscle function that frequently initiates in the limbs, called limb-onset ALS, or initiates in facial muscles, called bulbar-onset ALS. This book describes the current understanding of ALS symptoms, diagnosis, causes, and treatments. Initial symptoms vary in type of muscle dysfunction, intensity of symptoms, and speed of disease progression. Diagnosis requires loss of function in both upper and lower motor neurons for limb- and bulbar-onset ALS, distinguishing ALS from other neuromuscular diseases. Although no cause or initial trigger has been determined for ALS, eventually both limb and bulbar muscles will show dysfunction as the disease progresses. In later stages of the disease, muscle dysfunction typically leads to respiratory failure and death. Management of neurotransmitter levels in patients can prolong life by months, but no cure exits for the disease. Other treatments exist that can help patients manage muscle weakness or spasms as the disease progresses. The book concludes by considering future detection, treatment, and diagnostic approaches with the goal of preventing disease initiation or progression. 410 0$aHuman diseases and conditions collection. 606 $aAmyotrophic lateral sclerosis 606 $aAmyotrophic Lateral Sclerosis 608 $aLibros electronicos. 610 $aamyotrophic lateral sclerosis (ALS) 610 $aLou Gehrig's disease 610 $amotor neuron disease 610 $aneuromuscular junction 610 $alimb-onset ALS 610 $abulbar-onset ALS 610 $amuscle weakness 615 0$aAmyotrophic lateral sclerosis. 615 2$aAmyotrophic Lateral Sclerosis. 676 $a616.83 700 $aMiller$b Mary E.$0940760 801 0$bFINmELB 801 1$bFINmELB 906 $aBOOK 912 $a9910136584103321 996 $aNerve disease ALS and gradual loss of muscle function$92121485 997 $aUNINA