LEADER 04482nam 2200565 450 001 9910136529303321 005 20170920010705.0 010 $a0-323-46278-2 035 $a(CKB)3710000000840762 035 $a(EBL)4658778 035 $a(MiAaPQ)EBC4658778 035 $a(EXLCZ)993710000000840762 100 $a20160908h20162016 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 00$aGastrointestinal neoplasia /$feditors, Paul J. Limburg, Dan A. Dixon ; consulting editor, Gary W. Falk 210 1$aPhiladelphia, Pennsylvania :$cElsevier,$d2016. 210 4$dİ2016 215 $a1 online resource (228 p.) 225 1 $aGastroenterology Clinics of North America,$x0889-8553 ;$vVolume 45, Number 3 300 $aIncludes index. 300 $a"Clinics Review Articles"--Cover. 311 $a0-323-46257-X 327 $aTitle page; Table of Contents; Copyright; Contributors; Forthcoming Issues; Preface; Esophageal Cancer; Key points; Introduction; Squamous cell carcinoma of the esophagus; Adenocarcinoma of the esophagus; Barrett's esophagus; Diagnosis; Staging; Treatment; The future of diagnosis and management; Other esophageal malignancies; Summary; Supplementary data; Current Perspectives on Gastric Cancer; Key points; Global impact of gastric cancer; Gastric cancer causes and risk factors; Gastric cancer classification; Gastric cancer prevention; Screening and surveillance; Diagnostic evaluation 327 $aClinical managementPrognosis and survivorship; Pancreatic Cancer: A Review; Key points; Introduction and public health concerns; Molecular pathways/genetics; Risk factors; Early detection; Diagnostic evaluation; Clinical management; Surgery; Chemotherapy; Survivorship; Future directions; Summary; Small Bowel Adenocarcinoma; Key points; Introduction; Epidemiology; Tumor phenotyping; Risk factors for small bowel adenocarcinoma; Diagnosis of small bowel adenocarcinoma; Prognosis; Treatment; Summary; Colorectal Cancer: Genetics is Changing Everything; Key points; Introduction; Molecular pathways 327 $aPublic health burdenRisk and protective factors; Screening and early detection; Diagnostic evaluation; Prognosis; Clinical management; Survivorship; Knowns and Known Unknowns of Gastrointestinal Stromal Tumor Adjuvant Therapy; Key points; Introduction; Case series from the era before imatinib therapy; Selected trials of adjuvant imatinib; Z9000 (1-year imatinib); Z9001 (0 vs 1-year adjuvant imatinib); European Organisation for Research and Treatment of Cancer intergroup trial (0 vs 2-year adjuvant imatinib) 327 $aScandinavian Sarcoma Group XVIII/Arbeitsgemeinschaft Internistische Onkologie (1- vs 3-year adjuvant imatinib)Ongoing adjuvant trials; Neoadjuvant therapy; Reimaging; Sensitivity of gastrointestinal stromal tumor-specific KIT and PDGFRA mutations to imatinib; National and international guidelines; Commentary; Neuroendocrine Tumors; Key points; Introduction; Clinical presentations of gastroenteropancreatic neuroendocrine tumors; Diagnostic modalities; Markers of neuroendocrine tumors disease; Management; Summary; Heritable Gastrointestinal Cancer Syndromes; Key points; Genes and cancer 327 $aColorectal cancerColonic polyposis syndromes; Gastric cancer; Pancreatic adenocarcinoma; Clinical approach to genetic risk assessment for gastrointestinal cancer risk; Molecular Detection of Gastrointestinal Neoplasia: Innovations in Early Detection and Screening; Key points; Introduction; Mechanisms, media, and markers; A glimpse at emergent and experimental new molecular tools for gastrointestinal cancer screening; Summary; The Role of the Microbiome in Gastrointestinal Cancer; Key points; Introduction; Gastric cancer; Helicobacter pylori 327 $aBacterial and host factors affecting the propensity toward gastric cancer 410 0$aGastroenterology clinics of North America ;$vVolume 45, Number 3. 606 $aEndoscopy 606 $aEndoscopes 606 $aGastroenterology 615 0$aEndoscopy. 615 0$aEndoscopes. 615 0$aGastroenterology. 676 $a616.3307545 702 $aLimburg$b Paul J. 702 $aDixon$b Dan A. 702 $aFalk$b Gary W. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910136529303321 996 $aGastrointestinal neoplasia$93404638 997 $aUNINA