LEADER 03812oam 2200601 450 001 9910136404403321 005 20230621135826.0 010 $a9782889193448$b(ebook) 035 $a(CKB)3710000000612056 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/46349 035 $a(EXLCZ)993710000000612056 100 $a20191103h20152015 fy 0 101 0 $aeng 135 $aur||#|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aEndoplasmic reticulum - shape and function in stress translation /$ftopic editors, Lorenzo Frigerio, Federica Brandizzi, Stephen H. Howell and Patrick Schäfer 210 $cFrontiers Media SA$d2015 210 1$a[Lausanne, Switzerland] :$cFrontiers Media SA,$d[2015] 210 4$d©2015 215 $a1 online resource (110 pages) $cillustrations (black and white, and colour); digital file(s) 225 1 $aFrontiers Research Topics 300 $a"Published in: Frontiers in Plant Science" -- front cover. 311 08$aPrint version: 2889193446 320 $aIncludes bibliographical references. 330 $aThe endoplasmic reticulum (ER) is a manufacturing unit in eukaryotic cells required for the synthesis of proteins, lipids, metabolites and hormones. Besides supporting cellular signalling networks by its anabolic function, the ER on its own or in communication with other organelles directly initiates signalling processes of physiological significance. Based on the intimate and immediate involvement in stress signalling the ER is considered as sensory organelle on which cells strongly rely to effectively translate environmental cues into adaptive stress responses. The transcellular distribution of the ER providing comprehensive cell-to-cell connections in multicellular organisms probably allows a concerted action of cell alliances and tissue areas towards environmental constraints. At the cellular level, stress adaptation correlates with the capability of the ER machinery to synthesise proteins participating in stress signalling as well as in the activation of ER membrane localised proteins to start cell-protective signalling processes. Importantly, depending on the stress insult, the ER either supports protective strategies or initiates cell death programmes. Recent, genetic, molecular and cell biological studies have drawn an initial picture of underlying signalling events activated by ER membrane localised proteins. In this Research Topic, we will provide a platform for articles describing research on ER morphology and metabolism with a focus on stress translation. The Research Topic will be sub-divided into the following sections: 1. ER in stress signalling and adaptation; 2. ER structure and biosynthetic functions; 3. Regulation of protein processing; 4. Regulation of programmed cell death. 410 0$aFrontiers research topics. 606 $aEndoplasmic reticulum 606 $aBotany 606 $aEndoplasmic Reticulum Stress 610 $aMyosins 610 $acysteine endopeptidase 610 $aER associated degradation 610 $aUnfolded Protein Response 610 $aER bodies 610 $aprogrammed cell death 610 $abZIP transcription factors 610 $acaspase 615 0$aEndoplasmic reticulum. 615 0$aBotany. 615 2$aEndoplasmic Reticulum Stress. 676 $aE 700 $aFederica Brandizzi$4auth$01366879 702 $aSchäfer$b Patrick 702 $aFrigerio$b Lorenzo 702 $aBrandizzi$b Federica 702 $aHowell$b Stephen H$g(Stephen Herbert),$f1941- 801 0$bUkMaJRU 906 $aBOOK 912 $a9910136404403321 996 $aEndoplasmic reticulum - shape and function in stress translation$93389398 997 $aUNINA