LEADER 00871nam0-2200301 --450 001 9910332860403321 005 20190826123215.0 010 $a978-88-6677-315-3 020 $aIT$b2013-4896 100 $a20190826d2013----kmuy0itay5050 ba 101 0 $aita 102 $aIT 105 $a 001yy 200 1 $a<>nuova galassia McLuhan$evivere l'implosione del pianeta$fGianpiero Gamaleri 210 $aRoma$cArmando$d2013 215 $a221 p.$cill.$d20 cm 225 1 $aComunicazione e m@ss-media 320 $aContiene bibl. (pp.213-217) 610 0 $aMcLuhan, Marshall 676 $a302.23092$v22$zita 700 1$aGamaleri,$bGianpiero$0144441 801 0$aIT$bUNINA$gREICAT$2UNIMARC 901 $aBK 912 $a9910332860403321 952 $aIX B190$b1082/2019$fFSPBC 959 $aFSPBC 996 $aNuova galassia McLuhan$91558929 997 $aUNINA LEADER 03010nam 2200433z- 450 001 9910136390303321 005 20210211 035 $a(CKB)3710000000612022 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/55431 035 $a(oapen)doab55431 035 $a(EXLCZ)993710000000612022 100 $a20202102d2015 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aOrigin and spatiotemporal dynamics of the peroxisomal endomembrane system 210 $cFrontiers Media SA$d2015 215 $a1 online resource (148 p.) 225 1 $aFrontiers Research Topics 311 08$a2-88919-464-7 330 $aThe peroxisome is an organelle with essential roles in lipid metabolism, maintenance of reactive oxygen species homeostasis, and anaplerotic replenishment of tricarboxylic acid cycle intermediates destined for mitochondria. Peroxisomes constitute a dynamic endomembrane system. The homeostatic state of this system is upheld via two pathways for assembling and maintaining the diverse peroxisomal compartments constituting it; the relative contribution of each pathway to preserving such system may vary in different organisms and under various physiological conditions. One pathway begins with the targeting of certain peroxisomal membrane proteins to an endoplasmic reticulum template and their exit from the template via pre-peroxisomal carriers; these carriers mature into metabolically active peroxisomes containing the entire complement of membrane and matrix proteins. Another pathway operates via growth and maturation of pre-existing peroxisomal precursors that do not originate from the endoplasmic reticulum; mature peroxisomes proliferate by undergoing fission. Recent studies have uncovered new roles for the peroxisomal endomembrane system in orchestrating important developmental decisions and defining organismal longevity. This Frontiers Special Topic Issue is focused on the advances in our understanding of how evolutionarily distant organisms coordinate the formation, maturation, proliferation, maintenance, inheritance and quality control of the peroxisomal endomembrane system and how peroxisomal endomembranes communicate with other cellular compartments to orchestrate complex biological processes and various developmental programs from inside the cell. 606 $aPhysiology$2bicssc 610 $aAging 610 $adevelopment 610 $aEndoplasmic Reticulum 610 $aLipid Metabolism 610 $aperoxisomal endomembrane system 610 $aperoxisome 610 $aperoxisome biogenesis 610 $aReactive Oxygen Species 615 7$aPhysiology 700 $aRichard A. Rachubinski$4auth$01309748 702 $aVladimir I. Titorenko$4auth 906 $aBOOK 912 $a9910136390303321 996 $aOrigin and spatiotemporal dynamics of the peroxisomal endomembrane system$93029556 997 $aUNINA