LEADER 02323oam 2200625 450 001 9910136389903321 005 20230621141106.0 010 $a9782889193509 010 $a2889193500 035 $a(CKB)3710000000612024 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/62540 035 $a(EXLCZ)993710000000612024 100 $a20191103h20142014 fy| 0 101 0 $aeng 135 $aurc|#---||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aWays to improve tumor uptake and penetration of drugs into solid tumors /$ftopic editors: Fabrizio Marcucci, Angelo Corti and Ronald Berenson 210 $cFrontiers Media SA$d2014 210 1$a[Lausanne, Switzerland] :$cFrontiers Media SA,$d[2014] 210 4$dİ2014 215 $a1 online resource (129 pages) $cillustrations; digital file(s) 225 0 $aFrontiers in oncology 225 1 $aFrontiers Research Topics 320 $aIncludes bibliographical references. 330 $aThe main scope of this topic is to give an update on pharmacologic and non-pharmacologic approaches to enhance uptake and penetration of cancer drugs into tumors. Inadequate accumulation of drugs in tumors has emerged over the last decade as one of the main problems underlying therapeutic failure and drug resistance in the treatment of cancer. 410 0$aFrontiers research topics. 517 1 $aWays to improve tumour uptake and penetration of drugs into solid tumours 606 $aNeoplasms 606 $aTumors 606 $aOncology 606 $aCancer$xDrug testing 610 $aResistance 610 $amicroenvironment 610 $aAdministration 610 $atargeting 610 $aPenetration 610 $aDrug delivery 610 $aPermeability 610 $aJunctions 610 $aCancer 610 $aIntegrins 615 0$aNeoplasms. 615 0$aTumors. 615 0$aOncology. 615 0$aCancer$xDrug testing. 700 $aRonald Berenson$4auth$01366154 702 $aMarcucci$b Fabrizio 702 $aCorti$b Angelo 702 $aBerenson$b Ronald 801 0$bUkMaJRU 912 $a9910136389903321 996 $aWays to improve tumor uptake and penetration of drugs into solid tumors$93388677 997 $aUNINA