LEADER 03606nam 2200697 450 001 9910136281003321 005 20230621141347.0 035 $a(CKB)3710000000586910 035 $a(SSID)ssj0001684432 035 $a(PQKBManifestationID)16517428 035 $a(PQKBTitleCode)TC0001684432 035 $a(PQKBWorkID)15045162 035 $a(PQKB)10274698 035 $a(WaSeSS)IndRDA00056919 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/55362 035 $a(EXLCZ)993710000000586910 100 $a20160829d2015 fy 0 101 0 $aeng 135 $aur||#|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 04$aThe oral microbiome in an ecological perspective /$fedited by Egija Zaura and Alex Mira 210 $cFrontiers Media SA$d2015 210 31$a[Lausanne, Switzerland] :$cFrontiers Media SA,$d[2015] 210 4$dİ2015 215 $a1 online resource (116 pages) $cillustrations; digital file(s) 225 0 $aFrontiers Research Topics,$x1664-8714 300 $aBibliographic Level Mode of Issuance: Monograph 300 $a"Published in: Frontiers in cellular and infection microbiology" -- front cover. 311 08$aPrint version: 2889195767 320 $aIncludes bibliographical references. 330 $aThe oral cavity harbors an immense diversity of microorganisms, including bacteria, fungi, archaea, protozoa and viruses. At health, oral microbial community is thought to be in a state of homeostasis, even after numerous perturbations (e.g., toothbrushing, food intake) a day. The breach in this homeostasis can occur for instance if the perturbations become too excessive (e.g., frequent carbohydrate intake leading to acidification of the community) or the host is compromised (e.g., inadequate immune response resulting in persistent inflammation of periodontal tissue). Aggressive antimicrobial therapy (e.g., antibiotics in case of periodontal disease or preventive antibiotic therapy before and after dental extractions) is commonly applied with all the negative consequences of this approach. So far little is known on the interplay between the environmental, host and microbial factors in maintaining an ecological balance. What are the prerequisites for a healthy oral ecosystem? Can we restore an unbalanced oral microbiome? How stable is the oral microbiome through time and how robust it is to external perturbations? Gaining new insights in the ecological factors sustaining oral health will lead to conceptually new therapies and preventive programs. 410 0$aFrontiers research topics. 606 $aQuorum sensing (Microbiology) 606 $aCommunicable diseases 606 $aMicrobiology & Immunology$2HILCC 606 $aBiology$2HILCC 606 $aHealth & Biological Sciences$2HILCC 610 $aOral ecology 610 $aQuorum Sensing 610 $aImmune System 610 $ametatranscriptomics 610 $aBiofilm 610 $ahorizontal gene transfer 610 $aFungal bacterial interactions 610 $aDental Plaque 615 0$aQuorum sensing (Microbiology) 615 0$aCommunicable diseases. 615 7$aMicrobiology & Immunology 615 7$aBiology 615 7$aHealth & Biological Sciences 700 $aEgija Zaura$4auth$01364865 702 $aMira$b Alex 702 $aZaura$b Egija$f1971- 801 0$bPQKB 801 2$bUkMaJRU 906 $aBOOK 912 $a9910136281003321 996 $aThe oral microbiome in an ecological perspective$93386308 997 $aUNINA