LEADER 03475oam 2200481I 450 001 9910136246703321 005 20230808200137.0 010 $a1-315-34122-0 010 $a1-315-36487-5 010 $a981-4669-19-9 024 7 $a10.1201/9781315364872 035 $a(CKB)3710000000915764 035 $a(MiAaPQ)EBC5209704 035 $a(MiAaPQ)EBC4951156 035 $a(OCoLC)944502257 035 $a(Au-PeEL)EBL4951156 035 $a(CaONFJC)MIL963603 035 $a(OCoLC)1024277110 035 $a(EXLCZ)993710000000915764 100 $a20180331h20162016 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aMicrorheology with optical tweezers $eprinciples and applications /$fedited by Manlio Tassieri 210 1$aSingapore :$cPan Stanford Publishing Pte. Ltd.,$d[2016] 210 4$d©2016 215 $a1 online resource (xvi, 312 pages) $cillustrations 311 $a981-4669-18-0 327 $apart 1. Introduction -- part 2. Optical tweezers -- part 3. microrheology. 330 $aThanks to the pioneering works of Ashkin and coworkers, optical tweezers (OTs) have become an invaluable tool for myriad studies throughout the natural sciences. Their success relies on the fact that they can be considered as exceptionally sensitive transducers that are able to resolve pN forces and nm displacements, with high temporal resolution, down to µs. Hence their application to study a wide range of biological phenomena such as measuring the compliance of bacterial tails, the forces exerted by a single motor protein, and the mechanical properties of human red blood cells and of individual biological molecules. The number of articles related to them totals to a whopping 58,000 (source Google Scholar)!Microrheology is a branch of rheology, but it works at micrometer length scales and with microliter sample volumes. Therefore, microrheology techniques have been revealed to be very useful tools for all those rheological/mechanical studies where rare or precious materials are employed, such as in biological and biomedical studies.The aim of this book is to provide a pedagogical introduction to the physics principles governing both the optical tweezers and their application in the field of microrheology of complex materials. This is achieved by following a linear path that starts from a narrative introduction of the "nature of light," followed by a rigorous description of the fundamental equations governing the propagation of light through matter. Moreover, some of the many possible instrumental configurations are presented, especially those that better adapt to perform microrheology measurements. In order to better appreciate the microrheological methods with optical tweezers explored in this book, informative introductions to the basic concepts of linear rheology, statistical mechanics, and the most popular microrheology techniques are also 330 8 $agiven. Furthermore, an enlightening prologue to the general applications of optical tweezers different from rheological purposes is provided at the end of the book. 606 $aOptical tweezers 615 0$aOptical tweezers. 676 $a621.3692 702 $aTassieri$b Manlio 801 0$bFlBoTFG 801 1$bFlBoTFG 906 $aBOOK 912 $a9910136246703321 996 $aMicrorheology with optical tweezers$91999305 997 $aUNINA