LEADER 03526nam 2200613Ia 450 001 9910133575303321 005 20230725052459.0 010 $a1-283-37387-4 010 $a9786613373878 010 $a0-470-97788-4 010 $a0-470-97787-6 035 $a(CKB)3400000000000309 035 $a(EBL)661764 035 $a(OCoLC)705353426 035 $a(SSID)ssj0000476971 035 $a(PQKBManifestationID)11295637 035 $a(PQKBTitleCode)TC0000476971 035 $a(PQKBWorkID)10501836 035 $a(PQKB)10085002 035 $a(MiAaPQ)EBC661764 035 $a(Au-PeEL)EBL661764 035 $a(CaPaEBR)ebr10510343 035 $a(CaONFJC)MIL337387 035 $a(EXLCZ)993400000000000309 100 $a20101116d2011 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aChemical synthetic biology$b[electronic resource] /$feditors, Pier Luigi Luisi and Cristiano Chiarabelli 210 $aChichester, West Sussex, U.K. $cWiley$d2011 215 $a1 online resource (390 p.) 300 $aDescription based upon print version of record. 311 $a0-470-71397-6 320 $aIncludes bibliographical references and index. 327 $aChemical Synthetic Biology; Contents; List of Contributors; Introduction; Part One: Nucleic Acids; 1: Searching for Nucleic Acid Alternatives; 2: Never-Born RNAs : Versatile Modules for Chemical Synthetic Biology; 3: Synthetic Biology, Tinkering Biology, and Artificial Biology: A Perspective from Chemistry; 4: Peptide Nucleic Acids ( PNAs) as a Tool in Chemical Biology; Part Two: Peptides and Proteins; 5: High Solubility of Random-Sequence Proteins Consisting of Five Kinds of Primitive Amino Acids; 6: Experimental Approach for Early Evolution of Protein Function 327 $a7: Searching for de novo Totally Random Amino Acid SequencesPart Three: Complex Systems; 8: Synthetic Genetic Codes as the Basis of Synthetic Life; 9: Toward Safe Genetically Modified Organisms through the Chemical Diversification of Nucleic Acids; 10: The Minimal Ribosome; 11: Semi-Synthetic Minimal Living Cells; Part Four: General Problems; 12: Replicators: Components for Systems Chemistry; 13: Dealing with the Outer Reaches of Synthetic Biology Biosafety, Biosecurity, IPR, and Ethical Challenges of Chemical Synthetic Biology 327 $a14: The Synthetic Approach in Biology: Epistemological Notes for Synthetic BiologyIndex; Color Plates 330 $aChemistry plays a very important role in the emerging field of synthetic biology. In particular, chemical synthetic biology is concerned with the synthesis of chemical structures, such as proteins, that do not exist in nature. With contributions from leading international experts, Chemical Synthetic Biology shows how chemistry underpins synthetic biology. The book is an essential guide to this fascinating new field, and will find a place on the bookshelves of researchers and students working in synthetic chemistry, synthetic and molecular biology, bioengineering, systems biology, comput 606 $aBiomolecules$xSynthesis 606 $aBiochemistry 615 0$aBiomolecules$xSynthesis. 615 0$aBiochemistry. 676 $a572 701 $aLuisi$b P. L$0853443 701 $aChiarabelli$b Cristiano$0939834 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910133575303321 996 $aChemical synthetic biology$92119006 997 $aUNINA