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100   $a20100526d2010      uy             0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 00$aEnzyme technologies$b[electronic resource] $emetagenomics, evolution, biocatalysis, and biosynthesis /$fedited by Wu-Kuang Yeh, Hsiu-Chiung Yang, James R. McCarthy
210   $aHoboken, N.J. $cWiley$dc2010
215   $a1 online resource (390 p.)
225 1 $aChemical biology of enzymes for biotechnology and pharmaceutical applications ;$vv. 1
300   $aDescription based upon print version of record.
311   $a0-470-28624-5 
320   $aIncludes bibliographical references and index.
327   $aENZYME TECHNOLOGIES; CONTENTS; Contributors; Preface; PART A NEW APPROACHES TO FINDING AND MODIFYING ENZYMES; 1 Functional Metagenomics as a Technique for the Discovery of Novel Enzymes and Natural Products; 2 Directed Enzyme and Pathway Evolution; 3 Combining Natural Biodiversity and Molecular-Directed Evolution to Develop New Industrial Biocatalysts and Drugs; 4 Principles of Enzyme Optimization for the Rapid Creation of Industrial Biocatalysts; PART B BIOCATALYTIC APPLICATIONS; 5 Enzyme Catalysis in the Synthesis of Active Pharmaceutical Ingredients
327   $a6 Enzymatic Processes for the Production of Pharmaceutical Intermediates7 Novel Developments Employing Redox Enzymes: Old Enzymes in New Clothes; PART C BIOSYNTHETIC APPLICATIONS; 8 Drug Discovery and Development by Combinatorial Biosynthesis; 9 Reprogramming Daptomycin and A54145 Biosynthesis to Produce Novel Lipopeptide Antibiotics; 10 Pathway and Enzyme Engineering and Applications for Glycodiversification; Index
330   $a"Enzyme Technologies in Drug Discovery highlights how, what, and where enzymes have become critical in pharmaceutical and biotechnology research. This book provides in-depth reviews of recent developments in biosynthesis, biocatalysis, and the chemical biology of enzymes. This text discusses enzymatic assays, including emerging assay technologies for key enzyme classes in pharmaceutical research. In addition to new developments in proteomics, this book includes two emerging technologies in life sciences, metabolomics and preclinomics. This volume reviews important progress on the chemical biology of enzymes in the post-genomic era"--$cProvided by publisher.
410  0$aChemical biology of enzymes for biotechnology and pharmaceutical applications ;$vv. 1.
606   $aEnzymes$xBiotechnology
606   $aPharmaceutical biotechnology
615  0$aEnzymes$xBiotechnology.
615  0$aPharmaceutical biotechnology.
676   $a660.6/34
701   $aYeh$b Wu-Kuang$f1942-$0911817
701   $aYang$b Hsiu-Chiung$0911816
701   $aMcCarthy$b James R.$f1943-$0992854
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910132377603321
996   $aEnzyme technologies$92273550
997   $aUNINA