LEADER 05433nam 2200685 450 001 9910132171203321 005 20200520144314.0 010 $a3-527-67815-8 010 $a3-527-67813-1 010 $a3-527-67816-6 035 $a(CKB)3710000000216029 035 $a(EBL)1760764 035 $a(SSID)ssj0001412114 035 $a(PQKBManifestationID)11897528 035 $a(PQKBTitleCode)TC0001412114 035 $a(PQKBWorkID)11406988 035 $a(PQKB)10286418 035 $a(OCoLC)891397852 035 $a(MiAaPQ)EBC1760764 035 $a(Au-PeEL)EBL1760764 035 $a(CaPaEBR)ebr10905946 035 $a(CaONFJC)MIL635745 035 $a(OCoLC)886116745 035 $a(PPN)196493382 035 $a(EXLCZ)993710000000216029 100 $a20140819h20142014 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aInfrared and Raman spectroscopic imaging /$fedited by Reiner Salzer and Heinz W. Siesler 205 $aSecond, completely revised and updated edition. 210 1$aWeinheim, Germany :$cWiley-VCH,$d2014. 210 4$dİ2014 215 $a1 online resource (657 p.) 300 $aDescription based upon print version of record. 311 $a3-527-33652-4 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aInfrared and Raman Spectroscopic Imaging; Contents; Preface; List of Contributors; Part I Basic Methodology; Chapter 1 Infrared and Raman Instrumentation for Mapping and Imaging; 1.1 Introduction to Mapping and Imaging; 1.2 Mid-Infrared Microspectroscopy and Mapping; 1.2.1 Diffraction-Limited Microscopy; 1.2.2 Microscopes and Sampling Techniques; 1.2.3 Detectors for Mid-Infrared Microspectroscopy; 1.2.4 Sources for Mid-Infrared Microspectroscopy; 1.2.5 Spatial Resolution; 1.2.6 Transmission Microspectroscopy; 1.2.7 Attenuated Total Reflection Microspectroscopy 327 $a1.3 Raman Microspectroscopy and Mapping1.3.1 Introduction to Raman Microspectroscopy; 1.3.2 CCD Detectors; 1.3.3 Spatial Resolution; 1.3.4 Tip-Enhanced Raman Spectroscopy; 1.4 Near-Infrared Hyperspectral Imaging; 1.5 Raman Hyperspectral Imaging; 1.6 Mid-Infrared Hyperspectral Imaging; 1.6.1 Spectrometers Based on 2D Array Detectors; 1.6.2 Spectrometers Based on Hybrid Linear Array Detectors; 1.6.3 Sampling; 1.7 Mapping with Pulsed Terahertz Radiation; 1.8 Summary; Acknowledgments; References; Chapter 2 Chemometric Tools for Image Analysis; 2.1 Introduction 327 $a2.2 Hyperspectral Images: The Measurement2.2.1 The Data Set and the Underlying Model; 2.3 Image Preprocessing; 2.3.1 Signal Preprocessing; 2.3.1.1 De-noising; 2.3.1.2 Baseline Correction; 2.3.1.3 Detection and Suppression of Anomalous Pixels or Anomalous Spectral Readings; 2.3.2 Data Pretreatments; 2.3.3 Image Compression; 2.4 Exploratory Image Analysis; 2.4.1 Classical Image Representations: Limitations; 2.4.2 Multivariate Image Analysis (MIA) and Principal Component Analysis (PCA); 2.5 Quantitative Image Information: Multivariate Image Regression (MIR); 2.6 Image Segmentation 327 $a2.6.1 Unsupervised and Supervised Segmentation Methods2.6.2 Hard and Fuzzy Segmentation Approaches; 2.6.3 Including Spatial Information in Image Segmentation; 2.7 Image Resolution; 2.7.1 The Image Resolution Concept; 2.7.2 Spatial and Spectral Exploration; 2.7.3 The Resolution Process: Initial Estimates and Constraints; 2.7.4 Image Multiset Analysis; 2.7.5 Resolution Postprocessing: Compound Identification, Quantitative Analysis, and Superresolution; 2.7.5.1 Compound Identification; 2.7.5.2 Quantitative Analysis; 2.7.5.3 Superresolution; 2.8 Future Trends; References 327 $aPart II Biomedical ApplicationsChapter 3 Vibrational Spectroscopic Imaging of Soft Tissue; 3.1 Introduction; 3.1.1 Epithelium; 3.1.2 Connective Tissue and Extracellular Matrix; 3.1.3 Muscle Tissue; 3.1.4 Nervous Tissue; 3.2 Preparation of Soft Tissue for Vibrational Spectroscopic Imaging; 3.2.1 General Preparation Strategies; 3.2.2 Vibrational Spectra of Reference Material; 3.2.3 Preparation for FT-IR Imaging; 3.2.4 Preparation for Raman Imaging; 3.3 Applications to Soft Tissue; 3.3.1 Colon Tissue; 3.3.2 Brain Tissue and Brain Tumors; 3.3.2.1 Mouse Brains; 3.3.2.2 Primary Brain Tumors 327 $a3.3.2.3 Secondary Brain Tumors 330 $aThis second edition of the successful ready reference is updated and revised with approximately 30% new content to reflect the numerous instrumental developments and improvements, as well as the significant expansion of this rapidly developing field. For example, the combination of IR imaging with AFM has enhanced the achievable lateral resolution by an order of magnitude down to a few hundred nanometers, thus launching a multiplicity of new applications in material science. Furthermore, Raman and IR spectroscopic imaging have become key technologies for the life sciences and today contribute 606 $aInfrared spectroscopy 606 $aRaman spectroscopy 615 0$aInfrared spectroscopy. 615 0$aRaman spectroscopy. 676 $a543.08583 702 $aSalzer$b Reiner$f1942- 702 $aSiesler$b H. W. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910132171203321 996 $aInfrared and Raman spectroscopic imaging$91944908 997 $aUNINA