LEADER 01099nam 22003373 450 001 9910131728303321 005 20100305000000.0 035 $a(CKB)3460000000086759 035 $a(ItFiC)it 02448365 035 $a(EXLCZ)993460000000086759 100 $a20110322d2009 uy 0 101 0 $aita 200 10$aLingua e identità dell'immigrazione russofona in Italia /$fMonica Perotto 205 $a1. ed. italiana. 210 $aNapoli $cLiguori$d2009 215 $a178 p. ;$d24 cm 225 0$aDomini.$pMonografie del Dipartimento di scienze linguistiche e letterarie, Università degli studi G. d'Annunzio, Chieti-Pescara ;$v13 300 $aM. Perotto teaches at the University of Bologna. 311 $a88-207-4837-1 311 $a88-207-4948-3 320 $aIncludes bibliographical references. 676 $a304 676 $a305 676 $a491 676 $a306 700 $aPerotto$b Monica$0692951 801 0$bItFiC 906 $aBOOK 912 $a9910131728303321 996 $aLingua e identità dell'immigrazione russofona in Italia$92431021 997 $aUNINA LEADER 04064nam 22006255 450 001 9910369933103321 005 20251116220341.0 010 $a3-030-26439-4 024 7 $a10.1007/978-3-030-26439-0 035 $a(CKB)4100000009523019 035 $a(DE-He213)978-3-030-26439-0 035 $a(MiAaPQ)EBC5941798 035 $a(iGPub)SPNA0062691 035 $a(PPN)258851929 035 $a(EXLCZ)994100000009523019 100 $a20191011d2020 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aTumor Liquid Biopsies /$fedited by Florence Schaffner, Jean-Louis Merlin, Nikolas von Bubnoff 205 $a1st ed. 2020. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2020. 215 $a1 online resource (VI, 368 p.) 225 1 $aRecent Results in Cancer Research,$x0080-0015 ;$v215 311 08$a3-030-26438-6 320 $aIncludes bibliographical references. 327 $aCirculating Tumor Cells: Pathophysiology of Tumor Cell Release into the Circulation and characterization of CTC -- CTC enrichment technologies -- Genotyping of CTC :example Lung cancer -- CTC in Breast Cancer: a clinical approach -- Circulating Tumor DNA: Pathophysiology of ctDNA Release into the Circulation and its characterization -- Enrichment and Analysis of ctDNA -- ctDNA in Lung Cancer -- ctDNA in Breast Cancer -- ctDNA in Colorectal Cancer -- Dynamic Treatment Stratification using ctDNA -- Circulating Tumor RNA: Noncoding Tumor RNAs: Pathophysiology of Release and Techniques of Detection -- Circulating miRNAs as Biomarker in Cancer -- Plasma Subcompartments as Source for Tumor derived Biomarkers: Exosomes and Vesicles as Biomarker in Cancer -- Quantitative proteomic Analysis of Plasma in Cancer. 330 $aThis book is a comprehensive guide to the techniques, clinical applications, and benefits of the different forms of liquid biopsy employed in patients with a variety of tumor types, including lung, breast and colorectal cancer. Offering detailed explanations, it discusses the how changes in tumors can be tracked using these cutting-edge technologies, which enable the detection and analysis of diverse circulating biomarkers: tumor cells, tumor DNA, tumor RNA (free or in exosomes), and fluid biomarkers identifiable by means of targeted proteomics. The use of such advanced technologies is enabling us to tackle questions and problems in a way that was not possible just a few years ago. We now have at our disposal an effective means of overcoming the problem of intratumor heterogeneity, which has limited the value of conventional biopsy approaches. As a consequence, oncology practice is about to change radically, toward truly personalized precision medicine. This book provides both clinicians and researchers with a thorough and up-to-date overview of progress in the field. 410 0$aRecent Results in Cancer Research,$x0080-0015 ;$v215 606 $aOncology 606 $aPathology 606 $aCancer$xResearch 606 $aOncology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33160 606 $aPathology$3https://scigraph.springernature.com/ontologies/product-market-codes/H4800X 606 $aCancer Research$3https://scigraph.springernature.com/ontologies/product-market-codes/B11001 615 0$aOncology. 615 0$aPathology. 615 0$aCancer$xResearch. 615 14$aOncology. 615 24$aPathology. 615 24$aCancer Research. 676 $a616.994 676 $a616.994075 702 $aSchaffner$b Florence$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aMerlin$b Jean-Louis$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aBubnoff$b Nikolas von$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910369933103321 996 $aTumor Liquid Biopsies$92047276 997 $aUNINA