LEADER 02328nam 2200493 450 001 9910138410903321 005 20221018204324.0 010 $a953-51-4491-X 035 $a(CKB)3230000000076111 035 $a(NjHacI)993230000000076111 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/48197 035 $a(MiAaPQ)EBC30390365 035 $a(Au-PeEL)EBL30390365 035 $a(EXLCZ)993230000000076111 100 $a20221018d2011 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aFundamental and Advanced Topics in Wind Power /$fedited by Rupp Carriveau 205 $a1st ed. 210 $cIntechOpen$d2011 210 1$aRijeka, Croatia :$cIntechOpen,$d2011. 210 4$dİ2011 215 $a1 online resource (436 pages) $cillustrations 311 $a953-307-508-2 330 $aAs the fastest growing source of energy in the world, wind has a very important role to play in the global energy mix. This text covers a spectrum of leading edge topics critical to the rapidly evolving wind power industry. The reader is introduced to the fundamentals of wind energy aerodynamics; then essential structural, mechanical, and electrical subjects are discussed. The book is composed of three sections that include the Aerodynamics and Environmental Loading of Wind Turbines, Structural and Electromechanical Elements of Wind Power Conversion, and Wind Turbine Control and System Integration. In addition to the fundamental rudiments illustrated, the reader will be exposed to specialized applied and advanced topics including magnetic suspension bearing systems, structural health monitoring, and the optimized integration of wind power into micro and smart grids. 606 $aWind Power 610 $aEngineering 610 $aPhysical Sciences 610 $aEngineering and Technology 610 $aEnergy Engineering 610 $aSustainability Science 615 0$aWind Power. 676 $a621.312136 700 $aRupp Carriveau$4auth$01366147 702 $aCarriveau$b Rupp 801 0$bNjHacI 801 1$bNjHacl 906 $aBOOK 912 $a9910138410903321 996 $aFundamental and Advanced Topics in Wind Power$93388664 997 $aUNINA LEADER 01548oam 2200445zu 450 001 9910130691103321 005 20241212220405.0 010 $a9781467310369 010 $a1467310360 035 $a(CKB)3420000000000537 035 $a(SSID)ssj0000703676 035 $a(PQKBManifestationID)12304114 035 $a(PQKBTitleCode)TC0000703676 035 $a(PQKBWorkID)10692343 035 $a(PQKB)10786833 035 $a(NjHacI)993420000000000537 035 $a(EXLCZ)993420000000000537 100 $a20160829d2012 uy 101 0 $aeng 135 $aur||||||||||| 181 $ctxt 182 $cc 183 $acr 200 10$a2012 13th International Symposium on Quality Electronic Design 210 31$a[Place of publication not identified]$cIEEE$d2012 215 $a1 online resource $cillustrations 300 $aBibliographic Level Mode of Issuance: Monograph 311 08$a9781467310345 311 08$a1467310344 606 $aIntegrated circuits$xVery large scale integration$xComputer-aided design$vCongresses 606 $aIntegrated circuits$xVery large scale integration$xDesign and construction$vCongresses 615 0$aIntegrated circuits$xVery large scale integration$xComputer-aided design 615 0$aIntegrated circuits$xVery large scale integration$xDesign and construction 676 $a621.395 702 $aIEEE Staff 801 0$bPQKB 906 $aPROCEEDING 912 $a9910130691103321 996 $a2012 13th International Symposium on Quality Electronic Design$92495792 997 $aUNINA LEADER 03618nam 2200433z- 450 001 9910227348003321 005 20210211 035 $a(CKB)4100000000883853 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/54180 035 $a(oapen)doab54180 035 $a(EXLCZ)994100000000883853 100 $a20202102d2017 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aMyelin-Mediated Inhibition of Axonal Regeneration: Past, Present, and Future 210 $cFrontiers Media SA$d2017 215 $a1 online resource (116 p.) 225 1 $aFrontiers Research Topics 311 08$a2-88945-206-9 330 $aPioneering studies conducted in the 1980's laid the foundation for the hypothesis that axonal regeneration is limited by CNS myelin, and the identification of myelin-associated glycoprotein (MAG), Nogo, and oligodendrocyte myelin glycoprotein (OMgp) as inhibitors of neurite outgrowth firmly established myelin as a key factor in regenerative failure. Mechanistically, it has been shown that MAG, Nogo, and OMgp mediate inhibition by binding to either Nogo receptor (NgR) or paired immunoglobulin receptor B (PirB), and initiating a signaling cascade that culminates in the activation of RhoA. Since the discovery of these proteins, there has been tremendous interest in identifying compounds and molecular mechanisms that are capable of overcoming myelin-mediated inhibition. Many studies have focused on pharmacological antagonism of receptors and signaling intermediates, while others have sought to identify and enhance endogenous pro-regenerative pathways. The most notable example of the latter is the conditioning lesion effect, which led to the discovery of cyclic AMP's ability to overcome inhibition by MAG and myelin. Many of the agents tested in these studies have been shown to promote axonal regeneration in vivo, and this research topic allows researchers to share information about new treatments that have been developed in both academia and industry. As we look toward the future, it is becoming increasingly clear that reversal of myelin-mediated inhibition alone will not be sufficient to produce functional recovery from spinal cord injury, and that other factors, such as astroglial scarring, the expression of chondroitin sulfate proteoglycans, neuronal cell death, and lack of neurotrophic support, must also be taken into consideration. Combinatorial approaches therefore hold a great deal of promise, and we hope to initiate a dialogue on how stem cell transplantation, chondroitinase ABC, gene therapy, growth-promoting agents, and other methods can be combined to optimize functional recovery. We introduce this topic in honor of the life and work of Dr. Marie T. Filbin (1955-2014). Through these articles, we highlight past achievements in the field, novel findings, unanswered questions and innovative ideas that we hope will lead to new advances in axonal regeneration. 517 $aMyelin-Mediated Inhibition of Axonal Regeneration 606 $aNeurosciences$2bicssc 610 $aaxonal regeneration 610 $acAMP 610 $aCNS regeneration 610 $aMAG 610 $amyelin-associated inhibitors 610 $aNogo 610 $aOmgp 615 7$aNeurosciences 700 $aWilfredo Mellado$4auth$01288159 702 $aSari Hannila$4auth 906 $aBOOK 912 $a9910227348003321 996 $aMyelin-Mediated Inhibition of Axonal Regeneration: Past, Present, and Future$93020652 997 $aUNINA