LEADER 01211nam0-2200361---450- 001 990009398090403321 005 20110718091057.0 035 $a000939809 035 $aFED01000939809 035 $a(Aleph)000939809FED01 035 $a000939809 100 $a20110714g18781887km-y0itay50------ba 101 0 $ager 102 $aDE 105 $aa-------001yy 200 1 $aGefässsystem, Nervensystem und Sinnesorgane$fvon Carl Ernst Emil Hoffmann 210 $aErlangen$cEduard Besold$d1878-1887 215 $a3 v.$cill.$d26 cm 225 1 $aLehrbuch der Anatomie des Menschen$v2 327 1 $a1. - Gefässlehre / von Carl Ernst Emil Hoffmann. - 1878$a2. - Lehrbuch der Neurologie / von G. Schwalbe. - 1881$a3. - Die Lehre von den Sinnesorganen / von G. Schwalbe. - 1887 610 0 $aAnatomia umana 610 0 $aNeurologia 610 0 $aVasi sanguigni 610 0 $aOrgani di senso 700 1$aHoffmann,$bCarl Ernst Emil$0512013 701 1$aSchwalbe,$bG.$0512014 801 0$aIT$bUNINA$gRICA$2UNIMARC 901 $aBK 912 $a990009398090403321 952 $aIIIa C 82.2$b1290$fDMVSF 959 $aDMVSF 996 $aGefässsystem, Nervensystem und Sinnesorgane$9765250 997 $aUNINA LEADER 04211nam 22006495 450 001 9910755075703321 005 20231029011359.0 010 $a3-031-39171-3 024 7 $a10.1007/978-3-031-39171-2 035 $a(MiAaPQ)EBC30832478 035 $a(Au-PeEL)EBL30832478 035 $a(DE-He213)978-3-031-39171-2 035 $a(PPN)27291987X 035 $a(CKB)28572704500041 035 $a(EXLCZ)9928572704500041 100 $a20231028d2023 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aFerroptosis in Health and Disease /$fedited by Daolin Tang 205 $a2nd ed. 2023. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2023. 215 $a1 online resource (489 pages) 311 08$aPrint version: Tang, Daolin Ferroptosis in Health and Disease Cham : Springer International Publishing AG,c2023 9783031391705 327 $aChapter 1. Lipid Metabolism and Homeostasis in Ferroptosis -- Chapter 2. Iron Metabolism and Ferroptosis -- Chapter 3. Targeting Epigenetic Regulation of Ferroptosis in Cancer Therapy -- Chapter 4. The Role of Autophagy in Ferroptosis -- Chapter 5. Heat Shock Proteins and HSF1 in Ferroptosis -- Chapter 6. The Ongoing Search for a Biomarker of Ferroptosis -- Chapter 7. p53 and Ferroptosis -- Chapter 8. Ferroptosis in Cardiovascular Disease -- Chapter 9. Understanding Ferroptosis from a Free Radical Perspective -- Chapter 10. The NRF2-anti-ferroptosis Axis in Health and Disease -- Chapter 11. Epigenetic Modification in Ferroptosis -- Chapter 12. Organelle-specific Mechanisms of Ferroptosis -- Chapter 13. Ferroptosis: A Promising Therapeutic Target for Cardiovascular Diseases -- Chapter 14. Ferroptosis in Central Nervous System Hypoxia?Ischemia -- Chapter 15. Involvement of Ferroptosis in Lupus Nephritis -- Chapter 16. Ferroptosis and Infectious Diseases -- Chapter 17. Selenium Metabolic Pathway in Ferroptotic Cell Death -- Chapter 18. Epigenetic and Post-Translational Regulation of Ferroptosis -- Chapter 19. Phospholipid Peroxidation in Health and Disease -- Chapter 20 -- PKC?II?ACSL4 Axis Triggers Ferroptosis and Its Potential Implication in Ferroptosis-Related Diseases -- Chapter 21. Cancer Treatment with Ferroptosis by a Combination of Iron Nanoparticles and Gene Therapy -- Chapter 22. Inhibitors of Oxytosis/Ferroptosis: A New Class of Therapeutics for Alzheimer?s Disease. 330 $aThis updated and expanded volume gives new insights on ferroptosis ? an iron-dependent form of non-apoptotic cell death. The collection of chapters discusses the two major pathways through which ferroptosis can occur: the extrinsic or transporter-dependent pathway and the intrinsic or enzyme-regulated pathway. Readers will gain an understanding of the multiple levels, on which this special cell death is regulated. Hence, the contributions will take a closer look at epigenetic, transcriptional, posttranscriptional and posttranslational layers. Among the described regulators and transcription factors are GPX4, ACSL4 and NFE2L2. This edited volume collects reviews related to current knowledge on the integrated molecular machinery of ferroptosis, thereby also describing how dysregulated ferroptosis is involved in human diseases. 606 $aCytology 606 $aCell death 606 $aHuman physiology 606 $aProteins 606 $aStress (Physiology) 606 $aCell Biology 606 $aCell Death 606 $aHuman Physiology 606 $aProtein Biochemistry 606 $aCellular Stress 615 0$aCytology. 615 0$aCell death. 615 0$aHuman physiology. 615 0$aProteins. 615 0$aStress (Physiology) 615 14$aCell Biology. 615 24$aCell Death. 615 24$aHuman Physiology. 615 24$aProtein Biochemistry. 615 24$aCellular Stress. 676 $a571.936 700 $aTang$b Daolin$01435919 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910755075703321 996 $aFerroptosis in Health and Disease$93593966 997 $aUNINA