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Farooqui 205 $a1st ed. 210 $aHoboken, N.J. $cWiley$dc2012 215 $a1 online resource (434 p.) 300 $aDescription based upon print version of record. 311 08$a9781118001943 311 08$a111800194X 320 $aIncludes bibliographical references and index. 327 $aOxidative Stress In Vertebrates and Invertebrates: Molecular Aspects of Cell Signaling; Contents; Preface; Foreword; Acknowledgments; Contributors; Part I: Oxidative Stress in Vertebrates; 1: Generation of Reactive Oxygen Species in the Brain: Signaling for Neural Cell Survival or Suicide; 2: Free Radicals, Signal Transduction, and Human Disease; 3: Oxidative Stress and its Biochemical Consequences in Mitochondrial DNA Mutation-Associated Diseases: Implications of Redox Therapy for Mitochondrial Diseases 327 $a4: Oxidative Stress in Kainic Acid Neurotoxicity: Implications for the Pathogenesis of Neurotraumatic and Neurodegenerative Diseases5: Survival Strategy and Disease Pathogenesis According to the Nrf2-Small Maf Heterodimer; 6: Caloric Restriction and Oxidative Stress; 7: Pathogenesis of Neurodegenerative Diseases: Contribution of Oxidative Stress and Neuroinflammation; 8: Neurosteroids in Oxidative Stress-Mediated Injury in Alzheimer Disease; 9: Oxidative Stress in Adult Neurogenesis and in the Pathogenesis of Alzheimer Disease; 10: Oxidative Stress and Parkinson Disease 327 $a11: Oxidative Stress in Cardiovascular Diseases12: Oxidative Stress and Aging: A Comparison between Vertebrates and Invertebrates; 13: Oxidative Stress-Mediated Signaling Pathways by Environmental Stressors; 14: Selenoproteins in Cellular Redox Regulation and Signaling; 15: Antioxidant Therapy and its Effectiveness in Oxidative Stress-Mediated Disorders; 16: The Protective Role of Grape Seed Polyphenols Against Oxidative Stress in Treating Neurodegenerative Diseases; 17: Pharmacological and Therapeutic Properties of Propolis (Bee Glue); Part II: Oxidative Stress in Invertebrates 327 $a18: Endocrine Control of Oxidative Stress in Insects19: Oxidative Stress in the Airway System of the Fruit Fly Drosophila melanogaster; 20: Molecular Mechanisms of Antioxidant Protective Processes in Honeybee Apis mellifera; 21: Molecular Basis of Iron-induced Oxidative Stress in the Honeybee Brain: A Potential Model System of Olfactory Dysfunction in Neurological Diseases; 22: Modulation of Oxidative Stress by Keap1/Nrf2 Signaling in Drosophila: Implications for Human Diseases 327 $a23: Orchestration of Oxidative Stress Responses in Drosophila melanogaster: A Promoter Analysis Study of Circadian Regulatory Motifs24: The Protective Role of Sestrins Against Chronic TOR Activation and Oxidative Stress; 25: Current Advances in the Studies of Oxidative Stress and Age-Related Memory Impairment in C. elegans; 26: Oxidative Challenge and Redox Sensing in Mollusks: Effects of Natural and Anthropic Stressors; 27: Perspective and Directions for Future Studies; Index 330 $aThis volume presents a unique comparative treatment of the role oxidative stress plays in vertebrates and invertebrates in multiple organ systems with regards to cell death, development, aging, and human diseases, and anti-oxidant therapy. 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