LEADER 00942nam0-22003131i-450- 001 990006470490403321 005 20071128103657.0 010 $a2-8004-0708-5 035 $a000647049 035 $aFED01000647049 035 $a(Aleph)000647049FED01 035 $a000647049 100 $a20010426d1980----km-y0itay50------ba 101 0 $aita 105 $ay-------001yy 200 1 $a<>Europe et la coopération au développement$eun bilan la convention de Lomé$fPaule Bouvier$gpréf. de Henri Simonet 210 $aBruxelles$cEd. de l'Université de Bruxelles$d1980 215 $a191 p.$d24 cm 676 $a341.7 700 1$aBouvier,$bPaule$0124232 801 0$aIT$bUNINA$gRICA$2UNIMARC 901 $aBK 912 $a990006470490403321 952 $aDI 8/331$b6238$fDEC 952 $aXIV E 2813$b26692$fFSPBC 959 $aFSPBC 959 $aDEC 996 $aEurope et la coopération au développement$9652065 997 $aUNINA LEADER 01624nas 2200397 n 450 001 990008908740403321 005 20240229084438.0 011 $a1120-687X 035 $a000890874 035 $aFED01000890874 035 $a(Aleph)000890874FED01 035 $a000890874 091 $2CNR$aP 00139677 100 $a20161109a19909999km-y0itaa50------ba 101 0 $aita 102 $aIT 110 $aauu-------- 200 1 $aArchivio della nuova procedura penale 207 1$a1990- 210 $aPiacenza$cEditrice la Tribuna 326 $aBimestrale 452 0$12001$aArchivio della nuova procedura penale 530 0 $aArchivio della nuova procedura penale 675 $a43 675 $a343 676 $a345.45 801 0$aIT$bACNP$c20090723 859 4 $uhttp://acnp.cib.unibo.it/cgi-ser/start/it/cnr/dc-p1.tcl?catno=73573&person=false&language=ITALIANO&libr=&libr_th=unina1$zBiblioteche che possiedono il periodico 901 $aSE 912 $a990008908740403321 958 $aBiblioteca Centrale della Facoltà di Giurisprudenza dell'Università di Napoli Federico II$b1990-$ePer. it. 300$fFGBC 959 $aFGBC 996 $aArchivio della nuova procedura penale$9800267 997 $aUNINA AP1 8 $6866-01$aNA073 Biblioteca Centrale della Facoltà di Giurisprudenza dell'Università di Napoli Federico II$bPer. it. 300$eCorso Umberto I, 80138 Napoli (NA)$m0812537531/33$m0812537532$nit AP2 40$aacnp.cib.unibo.it$nACNP Italian Union Catalogue of Serials$uhttp://acnp.cib.unibo.it/cgi-ser/start/it/cnr/df-p.tcl?catno=73573&language=ITALIANO&libr=&person=&B=1&libr_th=unina&proposto=NO LEADER 04004nam 22004935 450 001 9910253868003321 005 20250609111221.0 010 $a3-319-32805-0 024 7 $a10.1007/978-3-319-32805-8 035 $a(CKB)3710000000717857 035 $a(DE-He213)978-3-319-32805-8 035 $a(MiAaPQ)EBC4533866 035 $a(PPN)194074390 035 $a(MiAaPQ)EBC6235629 035 $a(EXLCZ)993710000000717857 100 $a20160528d2016 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aProtein Targeting Compounds $ePrediction, Selection and Activity of Specific Inhibitors /$fedited by Thomas Böldicke 205 $a1st ed. 2016. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2016. 215 $a1 online resource (VIII, 288 p. 49 illus., 31 illus. in color.) 225 1 $aAdvances in Experimental Medicine and Biology,$x0065-2598 ;$v917 311 08$a3-319-32804-2 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aIntroduction -- Part I Methods of Structure Prediction -- Chapter 1 In Silico Prediction of Target-Inhibitor Interactions -- Part II Antibodies -- Chapter 2 Antibodies and Selection of Monoclonal Antibodies -- Chapter 3 Selection of Recombinant Human Antibodies -- Chapter 4 Selection of Recombinant Human Antibodies against Toxins and Viruses -- Chapter 5 Recent Advances with ER Targeted Intrabodies -- Chapter 6 Therapeutic Blocking Antibodies against Oncogenic Receptors and Growth Factors -- Chapter 7 Synthetic Cystine-Knot Miniproteins-Valuable Scaffolds for Polypeptide Engineering -- Part III Peptides, Small Molecules and Aptamers -- Chapter 8 Peptides and Peptide Analogs to Inhibit Protein -- Chapter 9 Allosteric Modulators of the Class A G Protein coupled Receptors -- Chapter 10 Phosphatases: Their Roles in Cancer and their Chemical Modulators -- Chapter 11 Selection and Application of Aptamers and Intramers -- Part IV Angiogenesis Inhibitors -- Chapter 12 Inhibitors of Angiogenesis. 330 $aThis book presents an overview of the most relevant protein knockdown techniques. Readers will find a description of the generation and use of recombinant human antibodies, ER intrabodies and peptides as well as a description of the working mechanism and potential of the inhibitory action of each of these molecules. The book will also describe the selection and activity of a number of phosphatases, aptamers and allosteric modulators, focusing on A G protein coupled receptors. The book starts with a chapter on the in silico prediction of target-inhibitor interactions. Key aspects of this book are: - Selection strategies for monoclonal and recombinant human antibodies - Selection strategies for ER intrabodies, peptides and aptamers - Examples of the most efficient inhibitors and their applications in protein biochemistry and cell biology - Antibodies for cancer therapy and inhibitors of angiogenesis. The book will be of great interest to scientists and students working in the life sciences on all areas related to protein biology. The variety of methods to modulate the activities of specific proteins which are introduced here will be of great benefit to the reader who is interested in general protein research or to readers who have very specific protein related questions. 410 0$aAdvances in Experimental Medicine and Biology,$x0065-2598 ;$v917 606 $aImmunology 606 $aImmunology$3https://scigraph.springernature.com/ontologies/product-market-codes/B14000 615 0$aImmunology. 615 14$aImmunology. 676 $a574.19296 702 $aBöldicke$b Thomas$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910253868003321 996 $aProtein Targeting Compounds$92528854 997 $aUNINA