LEADER 00888nam0-22003011i-450 001 990004596630403321 005 20170928114559.0 035 $a000459663 035 $aFED01000459663 035 $a(Aleph)000459663FED01 035 $a000459663 100 $a19990530d1956----km-y0itay50------ba 101 0 $ager$alat 102 $aNO 105 $ay-------001yy 200 1 $aSallust und seine Vorgaenger$eEine Sprachliche Untersuchung$feiliv Skard 210 $aOsloae$cIn Aedibus A.W. Brogger$d1956 215 $a110 p.$d22 cm 610 0 $aSallustio Crispo, Gaio$aOpere$aLinguaggio 676 $a878.01$v21$zita 700 1$aSkard,$bEiliv$0182323 801 0$aIT$bUNINA$gRICA$2UNIMARC 901 $aBK 912 $a990004596630403321 952 $aP2B 650 SALL. 8S.E. 1956$bBibl. 31020$fFLFBC 959 $aFLFBC 996 $aSallust und seine Vorgaenger$9550434 997 $aUNINA LEADER 05254nam 22006614a 450 001 9911020058503321 005 20200520144314.0 010 $a9786610722259 010 $a9781280722257 010 $a1280722258 010 $a9780470080122 010 $a0470080124 010 $a9780470080115 010 $a0470080116 035 $a(CKB)1000000000355237 035 $a(EBL)281572 035 $a(SSID)ssj0000112107 035 $a(PQKBManifestationID)11142574 035 $a(PQKBTitleCode)TC0000112107 035 $a(PQKBWorkID)10087219 035 $a(PQKB)11393200 035 $a(MiAaPQ)EBC281572 035 $a(OCoLC)85821184 035 $a(Perlego)2752650 035 $a(EXLCZ)991000000000355237 100 $a20060505d2007 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aBiomacromolecules $eintroduction to structure, function and informatics /$fC. Stan Tsai 210 $aHoboken, N.J. $cWiley-Liss$dc2007 215 $a1 online resource (770 p.) 300 $aDescription based upon print version of record. 311 08$a9780471713975 311 08$a047171397X 320 $aIncludes bibliographical references and index. 327 $aBIOMACROMOLECULES; CONTENTS; Preface; Abbreviations in Repetitive Use; CHAPTER 1 INTRODUCTION; 1.1 Prelude; 1.2 Covalent Bonds; 1.3 Noncovalent Interactions; 1.3.1 Electrostatic Interaction; 1.3.2 Van der Waals Interaction; 1.3.3 Hydrogen Bond; 1.3.4 Hydrophobic Interaction; 1.3.5 Steric Repulsion; 1.4 Isomerism: Configuration versus Conformation; 1.5 Trilogy; 1.6 References; CHAPTER 2 MONOMER CONSTITUENTS OF BIOMACROMOLECULES; 2.1 Nucleotides: Constituents of Nucleic Acids; 2.2 ?-Amino Acids: Constituents of Proteins; 2.3 Monosaccharides: Constituents of Glycans; 2.4 Addendum; 2.5 References 327 $aCHAPTER 3 PURIFICATION AND CHARACTERIZATION3.1 Purification: Overview; 3.2 Purification: Chromatography; 3.3 Purification: Electrophoresis; 3.4 Characterization: General; 3.4.1 Purity; 3.4.2 Molecular Weight; 3.4.3 Molecular Dimension; 3.5 Characterization: Specific; 3.5.1 Melting Temperature of DNA; 3.5.2 Buoyant Density of Biomacromolecules; 3.5.3 Isoelectric pH of Proteins; 3.5.4 Removal of Glycosides from Glycoproteins; 3.6 References; CHAPTER 4 BIOMACROMOLECULAR STRUCTURE: NUCLEIC ACIDS; 4.1 Structural Organization; 4.1.1 Structural Hierarchy 327 $a4.1.2 Representation of Structures of Nucleic Acids4.2 Sequence Analysis of Nucleic Acids; 4.2.1 General; 4.2.2 Chemical Cleavage Method; 4.2.3 Enzymatic Chain Termination/Dideoxy Method; 4.2.4 Mass Spectrometric Analysis; 4.2.5 Automated DNA Sequencing Technology; 4.3 Secondary Structure and Structure Polymorphism of DNA; 4.3.1 Key Structural Features of Nucleic Acids; 4.3.2 DNA Polymorphism; 4.3.3 Alternative Structures of DNA; 4.4 Supercoiling and Tertiary Structure of DNA; 4.4.1 DNA Topoisomers; 4.4.2 Superhelical Density and Energetics of Supercoiling. 327 $a4.5 Classification and Structures of RNA4.5.1 Structures of RNA; 4.5.2 Transfer RNA; 4.5.3 Ribosomal RNA; 4.5.4 Messenger RNA; 4.5.5 Other Classes of RNA; 4.6 RNA Folds and Structure Motifs; 4.6.1 RNA Folds; 4.6.2 Structure Motifs of RNA; 4.7 Energetics of Nucleic Acid Structure; 4.8 Nucleic Acid Application; 4.9 References; CHAPTER 5 BIOMACROMOLECULAR STRUCTURE: PROTEINS; 5.1 Architecture of Protein Molecules; 5.1.1 Introduction; 5.1.2 Representation of Protein Structures; 5.2 Primary Structure of Proteins: Chemical and Enzymatic Sequence Analysis; 5.2.1 Amino Acid Composition 327 $a5.2.2 Peptide Cleavage, Separation and Analysis5.2.3 Terminal and Sequence Determination; 5.2.4 Peptide Ladder Sequencing; 5.3 Primary Structure of Proteins: Sequence Analysis by Tandem Mass Spectrometry; 5.3.1 An Application of Mass Spectrometry (MS) in Protein Chemistry; 5.3.2 Application of Tandem Mass Spectrometry (MS-MS) in Protein Sequence Analysis; 5.4 Conformational Map; 5.5 Secondary Structures and Motifs of Proteins; 5.5.1 ?-Helical Structure; 5.5.2 ?-Sheet Structure; 5.5.3 Nonrepetitive Structure: Connection (Loop) and Turn; 5.5.4 Notes to Secondary Structures of Globular Proteins 327 $a5.5.5 Motifs: Supersecondary Structures 330 $aThis book provides an integrated treatment of the structure and function of nucleic acids, proteins, and glycans, including thorough coverage of relevant computational biochemistry. The text begins with an introduction to the biomacromolecules, followed by discussion of methods of isolation and purification, physiochemical and biochemical properties, and structural characteristics. The next section of the book deals with sequence analysis, analysis of conformation using spectroscopy, chemical synthesis, and computational approaches. The following chapters discuss biomolecular interactions, e 606 $aMacromolecules 606 $aBiomolecules 615 0$aMacromolecules. 615 0$aBiomolecules. 676 $a572/.33 700 $aTsai$b C. Stan$01838740 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9911020058503321 996 $aBiomacromolecules$94417795 997 $aUNINA