LEADER 00991nam0-22003011i-450 001 990001646010403321 005 20190529131316.0 035 $a000164601 035 $aFED01000164601 035 $a(Aleph)000164601FED01 035 $a000164601 100 $a20030910d1973----km-y0itay50------ba 101 0 $ager 102 $aCH 105 $ay-------001yy 200 1 $a<>Carnivoren des Steinheimer Beckens B. Ursidae, Felidae, Viverridae sowie Erganzungen und Nachtrage zu den Mustelidae$fElmar P.J. Heizmann 210 $aBasel$cBuchdruckerei Birkhäuser AG$d1973 215 $a9 p.$d24 cm 610 0 $aZoologia 676 $a591 700 1$aHeizmann,$bElmar P. J.$070791 801 0$aIT$bUNINA$gRICA$2UNIMARC 901 $aLG 912 $a990001646010403321 952 $a60 OP. 91/16$b44687$fFAGBC 959 $aFAGBC 996 $aCarnivoren des Steinheimer Beckens B. Ursidae, Felidae, Viverridae sowie Erganzungen und Nachtrage zu den Mustelidae$9372023 997 $aUNINA LEADER 03985oam 2200721I 450 001 9910457835803321 005 20200520144314.0 010 $a0-429-15227-2 010 $a1-280-12193-9 010 $a9786613525796 010 $a1-4398-3633-7 024 7 $a10.1201/b11523 035 $a(CKB)2550000000087901 035 $a(EBL)863087 035 $a(OCoLC)778448453 035 $a(SSID)ssj0000598641 035 $a(PQKBManifestationID)11369726 035 $a(PQKBTitleCode)TC0000598641 035 $a(PQKBWorkID)10610159 035 $a(PQKB)10300161 035 $a(MiAaPQ)EBC863087 035 $a(Au-PeEL)EBL863087 035 $a(CaPaEBR)ebr10531164 035 $a(CaONFJC)MIL352579 035 $a(OCoLC)785779620 035 $a(EXLCZ)992550000000087901 100 $a20180331d2012 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aBiodefense research methodology and animal models /$fedited by James R. Swearengen 205 $a2nd ed. 210 1$aBoca Raton :$cCRC Press,$d2012. 215 $a1 online resource (415 p.) 300 $aDescription based upon print version of record. 311 $a1-4398-3632-9 320 $aIncludes bibliographical references. 327 $aHistory of biological agents as weapons / James W. Martin -- Bioterrorism and biowarfare : similarities and differences / Nelson W. Rebert -- Scientific and ethical importance of animal models in biodefense research / James R. Swearengen and Arthur O. Anderson -- Development and validation of animal models / Jaime B. Anderson and Kenneth Tucker -- Infectious disease aerobiology : aerosol challenge methods / Chad J. Roy and Louise M. Pitt -- Characterization of new and advancement of existing animal models of bacillus anthracis infection / Elizabeth K. Leffel and Louise M. Pitt -- Glanders / David L. Fritz and David M. Waag -- Plague / Jeffery J. Adamovicz and Patricia L. Worsham -- Tularemia / Jeffery J. Adamovicz and David M. Waag -- Q fever / David M. Waag and David L. Fritz -- Brucellosis / Bret K. Purcell and Robert Rivard -- Alphaviruses / William D. Pratt ... [et al.] -- Orthopoxviruses / Peter B. Jahrling and Victoria Wahl-Jensen -- Animal models for viral hemorrhagic fevers / Kelly l. Warfield and Thomas W. Geisbert -- Botulinum toxins / Stephen B. Greenbaum, Jaime B. Anderson, and Frank J. Lebeda -- Ricin / Stephen B. Greenbaum and Jaime B. Anderson -- Staphylococcal and streptococcal superantigens : in vitro and in vivo assays / Teresa Krakauer and Bradley G. Stiles. 330 $aSignificant advances have been made in animal model development for biological research since the publication of the first edition of this volume, and the ramifications of the FDA's Animal Efficacy Rule have become better understood in the scientific community. With each chapter completely updated with the latest research findings, Biodefense Research Methodology and Animal Models, Second Edition spans the spectrum of coverage from basic research to advanced development of medical countermeasures.Topics discussed in this volume include:A history 606 $aBioterrorism$xPrevention$xResearch 606 $aInfection$xAnimal models 606 $aCommunicable diseases$xResearch 606 $aBiological weapons 606 $aAlternative toxicity testing 606 $aToxins$xResearch 608 $aElectronic books. 615 0$aBioterrorism$xPrevention$xResearch. 615 0$aInfection$xAnimal models. 615 0$aCommunicable diseases$xResearch. 615 0$aBiological weapons. 615 0$aAlternative toxicity testing. 615 0$aToxins$xResearch. 676 $a363.325/3 701 $aSwearengen$b James R$0987209 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910457835803321 996 $aBiodefense research methodology and animal models$92256343 997 $aUNINA