LEADER 00626nam0-22002291i-450- 001 990001307120403321 035 $a000130712 035 $aFED01000130712 035 $a(Aleph)000130712FED01 035 $a000130712 100 $a20000920d--------km-y0itay50------ba 101 1 $aeng 200 1 $aNonstandard analysis$eA Pratical Guide with Applications.$fby LUTZ R. - GOZE M. 700 1$aLutz,$bRobert$059234 801 0$aIT$bUNINA$gRICA$2UNIMARC 901 $aBK 912 $a990001307120403321 952 $aC-20-(881$b20572$fMA1 959 $aMA1 996 $aNonstandard analysis$9261845 997 $aUNINA DB $aING01 LEADER 04282nam 2200649 a 450 001 9910955983103321 005 20251017110057.0 010 $a0-309-22037-8 010 $a1-280-12331-1 010 $a9786613527172 010 $a0-309-22035-1 035 $a(CKB)2670000000176339 035 $a(EBL)3378943 035 $a(SSID)ssj0000646290 035 $a(PQKBManifestationID)11442329 035 $a(PQKBTitleCode)TC0000646290 035 $a(PQKBWorkID)10685990 035 $a(PQKB)10019381 035 $a(MiAaPQ)EBC3378943 035 $a(Au-PeEL)EBL3378943 035 $a(CaPaEBR)ebr10554787 035 $a(CaONFJC)MIL352717 035 $a(OCoLC)923289088 035 $a(DNLM)1583977 035 $a(EXLCZ)992670000000176339 100 $a20120509d2012 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt 182 $cc 183 $acr 200 10$aIntegrating large-scale genomic information into clinical practice $eworkshop summary /$fSteve Olson ... [et al.], rapporteurs ; Institute of Medicine of the National Academies 205 $a1st ed. 210 $aWashington, D.C. $cNational Academies Press$d2012 215 $a1 online resource (113 p.) 300 $aDescription based upon print version of record. 311 08$a0-309-22034-3 320 $aIncludes bibliographical references. 327 $a""Front Matter""; ""Reviewers""; ""Acknowledgments""; ""Contents""; ""Figures and Box""; ""Abbreviations and Acronyms""; ""1 Introduction""; ""2 The Realization of Genomic Medicine""; ""3 The Analysis of Genomic Data""; ""4 The Interpretation of Genomic Data""; ""5 The Delivery of Genomic Data""; ""6 Ethical and Legal Issues""; ""7 Workforce Development""; ""8 Envisioning the Future""; ""References""; ""Appendix A: Workshop Agenda""; ""Appendix B: Speaker Biographical Sketches""; ""Appendix C: Registered Attendees"" 330 $aThe initial sequencing of the human genome, carried out by an international group of experts, took 13 years and $2.7 billion to complete. In the decade since that achievement, sequencing technology has evolved at such a rapid pace that today a consumer can have his or her entire genome sequenced by a single company in a matter of days for less than $10,000, though the addition of interpretation may extend this time frame. Given the rapid technological advances, the potential effect on the lives of patients, and the increasing use of genomic information in clinical care, it is important to address how genomics data can be integrated into the clinical setting. Genetic tests are already used to assess the risk of breast and ovarian cancers, to diagnose recessive diseases such as cystic fibrosis, to determine drug dosages based on individual patient metabolism, and to identify therapeutic options for treating lung and breast tumors, melanoma, and leukemia. With these issues in mind and considering the potential impact that genomics information can have on the prevention, diagnosis, and treatment of disease, the Roundtable on Translating Genomic-Based Research for Health hosted a workshop on July 19, 2011, to highlight and identify the challenges and opportunities in integrating large-scale genomic information into clinical practice. Integrating large-scale genomic information into clinical practice summarizes the speaker presentations and the discussions that followed them. This report focuses on several key topics, including the analysis, interpretation, and delivery of genomic information plus workforce, ethical, and legal issues. 606 $aMedical genetics$xMethodology 606 $aGenomics 606 $aGenetic disorders$xEpidemiology 615 0$aMedical genetics$xMethodology. 615 0$aGenomics. 615 0$aGenetic disorders$xEpidemiology. 676 $a572.86 701 $aOlsen$b Steven$01602366 712 02$aInstitute of Medicine (U.S.).$bRoundtable on Translating Genomic-Based Research for Health. 712 02$aInstitute of Medicine (U.S.).$bBoard on Health Sciences Policy. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910955983103321 996 $aIntegrating large-scale genomic information into clinical practice$94447005 997 $aUNINA